Tertiary syphilis is a late phase of the sexually transmitted disease syphilis, caused by the spirochete Treponema pallidum. Below you may find medications used to treat or help with Tertiary Syphilis. More about Tertiary Syphilis

Tertiary Syphilis FAQ


What are the symptoms of tertiary syphilis?

Symptoms may include cardiovascular issues, such as aortic aneurysm, neurological problems like paralysis and sensory deficits, as well as skin manifestations such as gummatous lesions.

How is tertiary syphilis diagnosed?

Diagnosis is typically done through blood tests to detect antibodies to the syphilis bacteria, and in some cases, cerebrospinal fluid examination for neurological involvement.

Is tertiary syphilis curable?

Tertiary syphilis is treatable with antibiotics, although damage caused by the disease may not always be reversible. It's important to seek treatment as early as possible.

Can tertiary syphilis be transmitted sexually?

During the tertiary stage, the chances of transmission are low, but the infection can still be spread through sexual contact or from mother to unborn child during pregnancy.

What is the most common complication of tertiary syphilis?

Cardiovascular syphilis, including aortic aneurysm, is a common complication of tertiary syphilis, which can be life-threatening if not managed appropriately.

How long does the tertiary stage of syphilis last?

Tertiary syphilis can occur 3 to 15 years after initial infection, and the duration depends on the individual's response to treatment and the extent of organ involvement.

What medications are used to treat tertiary syphilis?

Antibiotics like penicillin G and doxycycline are commonly prescribed to treat tertiary syphilis, aiming to control the infection and prevent further complications.

Can untreated tertiary syphilis lead to death?

In severe cases, tertiary syphilis can lead to life-threatening complications such as cardiovascular issues or neurosyphilis. Seeking prompt treatment is essential.

Are there preventive measures for tertiary syphilis?

Practicing safe sex and getting tested for syphilis regularly can help prevent the progression to tertiary syphilis. Early detection and treatment are key in preventing complications.

What organs can be affected by tertiary syphilis?

Tertiary syphilis can affect various organs, including the heart leading to cardiovascular syphilis, the brain causing neurosyphilis, as well as other structures like the skin, bones, or liver.

Is there a risk of relapse after treatment for tertiary syphilis?

While treatment can effectively control the infection, there's a risk of relapse if not all bacteria are eliminated. It's crucial to follow the prescribed treatment regimen and attend follow-up appointments.

Can tertiary syphilis lead to mental health issues?

Neurosyphilis, a complication of tertiary syphilis, can manifest as cognitive and psychiatric symptoms such as dementia, personality changes, and mood disturbances.

What should one do if diagnosed with tertiary syphilis?

Seek medical treatment promptly and follow the healthcare provider's recommendations. Stay informed about the condition, take medications as prescribed, and attend follow-up appointments for monitoring.

Can tertiary syphilis cause vision problems?

Yes, ocular syphilis, a manifestation of neurosyphilis, can lead to various visual disturbances ranging from blurred vision to vision loss if not promptly addressed.

Are there any long-term effects of tertiary syphilis?

If left untreated, tertiary syphilis can have severe long-term effects such as damage to the heart, brain, or other organs, potentially leading to life-altering complications.

Can tertiary syphilis be prevented with vaccination?

Currently, there's no vaccine available to prevent syphilis. Practicing safe sex, being aware of the risk factors, and getting tested regularly are the primary preventive measures.

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Information provided by Dr. Tekeste Etay Teka. Reviewed by Dr. Mohamed El Khouly