Menopause & HRT

Menopause can bring vasomotor, genitourinary, mood, musculoskeletal and sexual symptoms, and hormone replacement therapy addresses these mainly with oestrogen, usually alongside a progestogen for anyone who still has a womb. Which combination suits someone depends on their symptoms and whether local or whole-body treatment is needed.

Offers

Provera

Medroxyprogesterone Acetate

2.5mg · 5mg · 10mg

Designed to support uterine safety to manage menstrual flow and alleviate risk of endometrial hyperplasia.

From$0.43/ tabletView

Estrace

Estradiol

1mg · 2mg

Indicated to address postmenopausal hormone depletion to relieve hot flashes and support structural bone mineral density.

From$1.45/ tabletView

Progesterone Capsules

Progesterone

200mg

Formulated to alleviate hormonal deficits to support healthy endometrial linings and target menstrual regularity.

From$0.69/ capsuleView

Duphaston

Dydrogesterone

10mg

Indicated to address localised endometrial balance to relieve painful menstrual irregularities and support pregnancy maintenance.

From$4.00/ tabletView

Tibofem

Tibolone

2.5mg

Designed to support estrogen receptor activation to manage menopausal hot flashes and alleviate bone loss.

From$2.79/ tabletView

Aygestin

Norethindrone Acetate

5mg

Utilised to manage endometrial lining growth to alleviate pelvic pain and support menstrual regularity.

From$1.17/ tabletView

Conjubrook

Conjugated Estrogens

0.625mg

Intended to relieve menopausal hot flashes to support comfort levels and target bone loss.

From$5.04/ tabletView

Estriol Topical

Estriol

Formulated to alleviate vaginal dryness to support local tissue integrity and target cellular mucosal layers.

From$22.20/ tubeView

About

Key points

NICE’s Recommendations | Menopause: identification and management guideline lists vasomotor, genitourinary, mood, musculoskeletal and sexual symptoms among those associated with menopause.
NHS’s Hormone replacement therapy (HRT) guidance sets out combined HRT, oestrogen-only HRT, vaginal oestrogen and tibolone as separate options depending on someone’s circumstances.

Oestrogen and tibolone for menopausal symptoms

Estrace contains estradiol and Conjubrook contains conjugated estrogens, both taken as tablets for menopausal vasomotor symptoms such as hot flushes. Estriol Topical contains estriol and is applied locally as a tube rather than swallowed, for vaginal dryness, discomfort during sex and other urogenital symptoms. Tibofem contains tibolone and is taken alone, without a separate oestrogen, for the same vasomotor symptoms and to help protect bone density after menopause.

Provera and Duphaston are not always menopause medicines

Provera contains medroxyprogesterone acetate and Progesterone Capsules contain progesterone, both listed for preventing endometrial hyperplasia, the womb-lining protection a progestogen provides once oestrogen is reintroduced. Duphaston (dydrogesterone) and Aygestin (norethindrone acetate) belong to the same ingredient group but are listed more for period problems such as endometriosis, abnormal uterine bleeding or a threatened miscarriage, not menopause. A progestogen prescription here can therefore mean either job.