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HIV ManagementHIV Management

HIV is treated with combinations of medicines from different drug classes, taken together as a regimen known as antiretroviral therapy. Which combination someone is prescribed depends on their treatment history, other health conditions and how the virus responds.

Tivicay

Dolutegravir

50mg

Formulated to alleviate retroviral disease to support immune preservation and target viral integrase enzymes.

From$8.18/ tabletView

Combivir

Lamivudine, Zidovudine

150mg + 300mg

Indicated to address systemic viral load to manage immune defense levels and target retroviral reverse transcription.

From$1.81/ tabletView

Epivir

Lamivudine

150mg

Intended to relieve retroviral replication to support cellular immune count recovery and target viral DNA polymerase.

From$1.51/ tabletView

Retrovir

Zidovudine

100mg · 300mg

Developed to mitigate retroviral progression to support CD4 cell count and target viral DNA polymerase.

From$0.73/ tabletView

Sustiva

Efavirenz

200mg · 600mg

Intended to relieve retroviral multiplication to support immune lymphocyte preservation and target reverse transcriptase.

From$5.31/ tabletView

Tenvir

Tenofovir Disoproxil

300mg

Developed to mitigate viral replication to support immune CD4 counts and target hepatitis B viral liver safety.

From$4.11/ tabletView

Famvir

Famciclovir

250mg · 500mg

Formulated to alleviate viral skin outbreaks to support immune defenses and target active viral DNA replication.

From$4.42/ tabletView

Kaletra

Lopinavir, Ritonavir

200mg + 50mg

Utilised to manage retroviral replication to support immune preservation and target viral protein assembly.

From$3.45/ tabletView

Viramune

Nevirapine

200mg

Utilised to manage retroviral replication to alleviate viral load and support chronic immune health.

From$1.61/ tabletView

Ziagen

Abacavir

300mg

Designed to support retroviral suppression to manage CD4 counts and target viral reverse transcription.

From$6.28/ tabletView

Videx Ec

Didanosine

100mg

Designed to support retroviral load management to manage CD4 cell levels and alleviate risk of opportunistic infections.

From$1.25/ tabletView

Zerit

Stavudine

30mg · 40mg

Utilised to manage retroviral replication to alleviate viral load and support chronic immune system safety.

From$0.20/ capsuleView

Indinavir Capsules

Indinavir

400mg

Formulated to alleviate retroviral disease to support immune cells and target active viral protein synthesis.

From$2.50/ capsuleView

Key points

  • CDC’s Treating HIV page recommends starting treatment as soon as possible after diagnosis, whatever someone’s health or how long they have had HIV.
  • The same page describes an undetectable viral load, reached through treatment, as preventing transmission of HIV through sex.
  • FDA’s HIV and AIDS: Medicines to Help You page groups HIV medicines into classes such as reverse transcriptase inhibitors, protease inhibitors and integrase inhibitors.

Single-tablet regimens with three ingredients

Biktarvy combines bictegravir, emtricitabine and tenofovir alafenamide in one tablet. Trustiva and Viraday both combine efavirenz, emtricitabine and tenofovir disoproxil, and Viropil combines dolutegravir, lamivudine and tenofovir disoproxil, each putting a three-ingredient regimen into one tablet.

Individual ingredients and two-part combinations

Tivicay contains dolutegravir and Sustiva contains efavirenz, from different drug classes. Epivir contains lamivudine and Retrovir contains zidovudine; Combivir combines the two in one tablet. Ziagen contains abacavir, Viramune contains nevirapine, and Kaletra combines lopinavir with ritonavir, alongside older options such as Indinavir Capsules, Zerit and Videx EC.

Tenvir-EM is also used to prevent HIV, not only to treat it

Tenvir-EM combines tenofovir disoproxil with emtricitabine and, unlike every other medicine here, is also used for pre-exposure prophylaxis: taken by someone without HIV to reduce the chance of acquiring it. The same tablet can treat or prevent HIV, depending on who takes it.

Famvir also appears in this group. It contains famciclovir and is used for herpes zoster, herpes simplex virus infections and chickenpox rather than HIV.

Further reading