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AntifungalsAntifungals

Fungal infections range from common skin, nail and vaginal infections to rare but serious invasive disease, and the form of a medicine, a cream, a tablet, a suppository or a nail lacquer, often matters as much as the ingredient itself.

Diflucan

Fluconazole

50mg · 100mg · 150mg · 200mg · 400mg

Formulated to alleviate fungal infections to support localised tissue healing and target fungal cell membrane synthesis.

From$1.13/ tabletView

Nizoral

Ketoconazole

200mg

Intended to relieve systemic fungal infections to support cellular tissue clearing and target fungal cell membrane synthesis.

From$1.46/ tabletView

Fulvicin

Griseofulvin

250mg

Indicated to address deep dermatophyte infections to relieve scalp and nail fungal scaling and support tissue clearance.

From$0.36/ tabletView

Micogel

Miconazole

2%

Formulated to alleviate dermal fungal infections to support skin barrier restoration and target cell membrane synthesis.

From$18.80/ tubeView

Nailrox Nail Lacquer

Ciclopirox

8%

Indicated to address localised fungal nail infections to relieve nail discoloration and support healthy nail structures.

From$31.33/ vialView

Lomexin

Fenticonazole

600mg

Intended to relieve vulvovaginal yeast infections to support vaginal tissue comfort and target fungal cells.

From$14.65/ suppositoryView

Mentax

Butenafine

15gm

Formulated to alleviate fungal skin infections to support dermal barrier integrity and target active mycelial membranes.

From$29.10/ tubeView

Luzu

Luliconazole

1%

Indicated to address superficial fungal infections to relieve dermal scale buildup and support healthy skin growth.

From$31.20/ tubeView

Vfend

Voriconazole

200mg

Developed to target serious fungal infections, this medication is indicated to address invasive aspergillosis and is utilised in systemic treatment protocols.

From$50.67/ tabletView

Key points

  • CDC’s About Fungal Diseases page describes topical, oral and intravenous antifungal medicines as all being in routine use, depending on where the infection sits.
  • CDC’s Clinical Care of Fungal Diseases: Antifungals groups antifungal medicines into classes such as azoles, echinocandins and polyenes according to how they act.

Luzu contains luliconazole, Mentax contains butenafine and Micogel contains miconazole, all creams for tinea pedis, tinea cruris and tinea corporis. Most tinea infections are treated this way, though Fulvicin is taken as a tablet, containing griseofulvin, for tinea capitis, tinea corporis and tinea pedis. Nailrox Nail Lacquer contains ciclopirox and is applied to the nail itself for onychomycosis and tinea pedis.

Vaginal candidiasis by mouth or applied locally

Diflucan contains fluconazole and treats vaginal candidiasis as a tablet taken by mouth, alongside systemic candidiasis and cryptococcal meningitis. Lomexin contains fenticonazole and treats vulvovaginal candidiasis as a suppository used locally rather than swallowed.

Vfend and Nizoral for deeper infections

Vfend contains voriconazole, used for invasive aspergillosis, candidaemia and oesophageal candidiasis. Nizoral contains ketoconazole, used for systemic fungal infections as well as tinea corporis and seborrhoeic dermatitis.

A caution with Lotrisone

Lotrisone combines clotrimazole with betamethasone dipropionate, a corticosteroid, for tinea cruris, tinea corporis and tinea pedis. CDC advises against this kind of antifungal and corticosteroid combination generally, since the steroid component can make a fungal infection worse rather than better.

Further reading