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Biologic and immunosuppressant medicines for autoimmune and inflammatory conditions, including Humira, Imuran, Prograf, Cellcept and Arava, used across rheumatology, organ transplant care and relapsing multiple sclerosis.

Humira

Adalimumab

20mg / 0.4ml · 40mg / 0.8ml

Adalimumab injectable solution for rheumatoid arthritis and psoriatic arthritis. A biologic that blocks TNF-alpha, a molecule that fuels joint inflammation.

From$285.38/ auto-injectorView

Imuran

Azathioprine

25mg · 50mg

Azathioprine tablets for rheumatoid arthritis and to prevent organ transplant rejection. It blocks the growth of white blood cells.

From$1.55/ tabletView

Prograf

Tacrolimus

0.5mg · 1mg · 5mg

Tacrolimus tablets to stop organ transplant rejection. It suppresses the immune system's attack on the new organ and requires regular blood level checks.

From$3.34/ tabletView

Cellcept

Mycophenolate Mofetil

250mg · 500mg

Mycophenolate mofetil capsules for preventing organ transplant rejection. It targets lymphocytes specifically, reducing the risk of the body attacking the new organ.

From$2.91/ capsuleView

Ciclosporin Capsules

Ciclosporin

50mg · 100mg

Ciclosporin capsules for rheumatoid arthritis and psoriasis. It suppresses T-lymphocyte activity by blocking a specific cell-signalling pathway.

From$4.10/ capsuleView

Arava

Leflunomide

10mg · 20mg

Leflunomide tablets for rheumatoid arthritis. It stays in the body for weeks after stopping, so side effects may persist long after the last dose.

From$1.90/ tabletView

Hsquin

Hydroxychloroquine

200mg · 300mg · 400mg

Hydroxychloroquine tablets for rheumatoid arthritis and lupus. It calms the immune system's attack on joints and tissues.

From$0.53/ tabletView

Aubagio

Teriflunomide

14mg

Teriflunomide tablets for relapsing remitting multiple sclerosis. It reduces the overactive immune response that damages nerve fibres in the brain and spinal cord.

From$205.67/ tabletView

Orapred

Prednisolone

2.5mg · 5mg · 10mg · 20mg · 40mg

Prednisolone tablets for rheumatoid arthritis and asthma. It mimics natural steroid hormones to damp down inflammation.

From$0.72/ tabletView

Key points

  • Adalimumab, the biologic in Humira, is used for several immune-mediated inflammatory conditions.
  • Azathioprine, the ingredient in Imuran, is an immunosuppressant used for autoimmune conditions and after organ transplantation.
  • Blood tests are an important part of monitoring azathioprine treatment.
  • Leflunomide and teriflunomide, the ingredients in Arava and Aubagio, are pyrimidine synthesis inhibitors.

Biologics, immunosuppressants and DMARDs in this range

Humira is a biologic that comes as an auto-injector, listed for rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn’s disease, ulcerative colitis and plaque psoriasis.

Prograf tablets, Cellcept and ciclosporin capsules add tacrolimus, mycophenolate mofetil and ciclosporin; these immunosuppressants are listed for organ transplant rejection, and ciclosporin is also listed for psoriasis. Azathioprine (Imuran) is the fourth immunosuppressant in the range, supplied as a tablet rather than a capsule.

Leflunomide (Arava) is listed for rheumatoid arthritis, while teriflunomide (Aubagio) is listed for relapsing forms of multiple sclerosis, including clinically isolated syndrome. Orapred, a prednisolone tablet, is also listed for rheumatoid arthritis, asthma and allergic reactions.

Further reading

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