Tamoxifen
Tamoxifen (Nolvadex) is an anti-oestrogen medicine used in the treatment of breast cancer. This listing includes Nolvadex and Tamoxifen Tablets, both tablet formulations containing tamoxifen.
Tamoxifen Tablets
Breast Cancer
20mg
Tamoxifen tablets for breast cancer. It blocks oestrogen that some breast cancers rely on to grow.
From$1.00/ tabletView
Key points
- Antioestrogen action: In breast cancer, tamoxifen blocks oestrogen from binding to oestrogen receptors in tumour tissue.
- Boxed warning: In risk-reduction use for women with DCIS or a high breast-cancer risk, tamoxifen citrate is associated with uterine cancers, stroke and pulmonary embolism; some events were fatal.
- Metabolism: Tamoxifen is broken down by CYP3A, CYP2C9 and CYP2D6 enzymes and inhibits P-glycoprotein, a transporter.
What tamoxifen is used for
Tamoxifen citrate is used for Breast Cancer that has spread, in women and men. It is also used in women with node-positive breast cancer after surgery and breast irradiation. For premenopausal women with metastatic breast cancer, it may be used as an alternative to ovarian removal or irradiation. Nolvadex is the originator brand in this catalogue, while Tamoxifen Tablets is another tablet listing for the same ingredient in Women’s Health.