Norwayz
Designed to support mitochondrial function to manage vision loss and alleviate cellular oxidative stress.
Norwayz details
- Condition
- Leber's Hereditary Optic Neuropathy
- Alternative names
- idebenone
- Therapeutic class
- Coenzyme Q10 Analog
- Pharmacological class
- Antioxidant
- Known off-label uses
- friedreich's ataxia
- Contraindications
- hypersensitivity to idebenone
- Minor side effects
- headache; nasopharyngitis; cough
- Moderate side effects
- mild diarrhoea; back pain; chromaturia
- Serious side effects
- severe neutropenia, requires immediate medical attention
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Manufacturer
- Intas Pharmaceuticals Ltd
- Onset Time
- 4–8 weeks
- Duration
- 12–24 hours
- Storage instructions
- Store below 25°C.
- Age restrictions
- Approved for patients over twelve years of age and adults.
Patient summary
designed to support mitochondrial function to manage vision loss and alleviate cellular oxidative stress.
Mechanism of action
Transfers electrons directly to complex III of the mitochondrial respiratory chain, bypassing damaged complex I to restore ATP synthesis.
Pregnancy and breastfeeding
TGA Category C: Limited clinical records. Avoid in pregnancy. Breastfeeding: Consult a doctor.