Norwayz
Idebenone tablets for Leber's hereditary optic neuropathy. It supports the energy-producing machinery inside cells rather than treating the eye directly.
Norwayz details
- Condition
- Leber's Hereditary Optic Neuropathy
- Alternative names
- idebenone
- Therapeutic class
- Coenzyme Q10 Analog
- Pharmacological class
- Antioxidant
- Known off-label uses
- friedreich's ataxia
- Contraindications
- hypersensitivity to idebenone
- Minor side effects
- headache; nasopharyngitis; cough
- Moderate side effects
- mild diarrhoea; back pain; chromaturia
- Serious side effects
- severe neutropenia, requires immediate medical attention
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Manufacturer
- Intas Pharmaceuticals Ltd
- Onset Time
- 4–8 weeks
- Duration
- 12–24 hours
- Storage instructions
- Store below 25°C.
- Age restrictions
- Approved for patients over twelve years of age and adults.
Patient summary
Idebenone tablets for Leber's hereditary optic neuropathy. It supports the energy-producing machinery inside cells rather than treating the eye directly.
Mechanism of action
Transfers electrons directly to complex III of the mitochondrial respiratory chain, bypassing damaged complex I to restore ATP synthesis.
Pregnancy and breastfeeding
Pregnancy: Limited clinical records. Avoid in pregnancy. Breastfeeding: Consult a doctor.