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Zanaflex Medication Information Leaflet

Common Use

Zanaflex (Tizanidine) is primarily used as a muscle relaxant to manage spasticity due to neurological conditions.

Clinical Use

Clinically, Zanaflex is used to treat conditions such as multiple sclerosis and spinal cord injuries, helping to alleviate muscle stiffness and spasms.

Generic Ingredient

Tizanidine is available as a generic version in the UAE.

Drug Classification

Zanaflex is classified as a centrally acting alpha-2 adrenergic agonist.

Spectrum Of Activity

Zanaflex has a specific activity against muscle spasticity, exerting effects primarily on the central nervous system.

Drug interaction

Zanaflex may interact with other medications, particularly those affecting the central nervous system such as antidepressants, opioids, and other muscle relaxants.

Dosage and Directions

The usual starting dose of Zanaflex is 2 mg, which can be taken up to three times a day depending on tolerance and clinical response.

Contraindications and Precautions

Zanaflex is contraindicated in patients with hypersensitivity to tizanidine and those with severe hepatic impairment. Caution is advised in patients with hypotension.

Possible side effect

Common side effects include drowsiness, dry mouth, and dizziness. More severe effects may include hypotension and liver issues.

Missed dose and Overdose

If a dose is missed, take it as soon as remembered unless it's almost time for the next dose. In case of overdose, seek emergency medical help.

Possible Risks

Risks include sedation and hypotension, particularly when used with other CNS depressants.

Storage

Zanaflex should be stored at room temperature, away from moisture and heat.

Special Cases

Use during pregnancy should be discussed with a healthcare professional. It is unclear if Zanaflex is excreted in breast milk.

Known Non-standard Use

Zanaflex has been used off-label for conditions such as insomnia and migraine prevention.

Certification Information

Zanaflex is approved in multiple countries, including the USA, Canada, and various EU countries.

Known Alternatives in UAE

Alternatives available in the UAE include Baclofen and Cyclobenzaprine.

Patient Considerations

Patients should be monitored for liver function and signs of sedation when starting to take Zanaflex.

Drug Popularity

Zanaflex is well-regarded among practitioners for managing spasticity and is frequently prescribed in the UAE.

Usage Statistics

Prescription rates for Zanaflex have been consistent due to the prevalence of conditions requiring muscle relaxants in the population.

Zanaflex FAQ

What is Zanaflex used for?

Zanaflex is primarily prescribed for the management of muscle spasticity resulting from conditions such as multiple sclerosis or spinal cord injuries. It acts as a muscle relaxant, helping reduce muscle tightness and discomfort.

How does Zanaflex work?

Zanaflex functions as an α2-adrenergic agonist, inhibiting presynaptic release of excitatory neurotransmitters. This mechanism helps to relax muscles and reduce spasms, allowing for increased mobility and comfort.

What are the side effects of Zanaflex?

Common side effects include drowsiness, dizziness, dry mouth, and fatigue. More severe reactions may include low blood pressure, liver complications, or allergic responses. It's essential to monitor for these effects, especially during the initial stages of treatment.

Can Zanaflex be taken with other medications?

Zanaflex may interact with other medications, particularly those that cause CNS depression, like alcohol or sedatives. Always consult your healthcare provider before combining Zanaflex with other treatments.

What is the recommended dosage of Zanaflex?

The typical starting dose for adults is 2 mg, taken at bedtime. The dosage may be adjusted based on individual response and tolerance, with a maximum recommended dose of 36 mg per day.

Is Zanaflex safe during pregnancy?

Zanaflex is categorized as a pregnancy category C drug, meaning risk to the fetus cannot be ruled out. It is crucial for pregnant or breastfeeding women to discuss their options with a healthcare provider.

How long does Zanaflex take to work?

Patients often report relief from muscle spasms within one to two hours after taking Zanaflex. The peak effect usually occurs in about 3 to 4 hours after administration.

Can Zanaflex cause withdrawal symptoms?

Discontinuation of Zanaflex can lead to withdrawal symptoms such as increased spasticity or rebound hypertension. It's advisable to taper off the medication under medical supervision rather than stopping abruptly.

Are there any dietary restrictions while taking Zanaflex?

While there are no specific dietary restrictions associated with Zanaflex, avoiding alcohol and foods that may exacerbate drowsiness can help reduce side effects.

Can Zanaflex be used for conditions other than muscle spasms?

Although primarily indicated for muscle spasticity, some healthcare providers may explore its off-label use for conditions like migraine or fibromyalgia, but this should always be guided by a professional.

What should I do if I miss a dose of Zanaflex?

If a dose of Zanaflex is missed, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular schedule. Never double the dose.

Is Zanaflex addictive?

Zanaflex is not classified as a controlled substance; however, long-term use can lead to psychological dependence. Careful monitoring and adherence to prescribed dosages can minimize the risk.

How should Zanaflex be stored?

Zanaflex should be stored at room temperature, away from moisture and heat. Keep it out of reach of children and pets, ensuring it's safely sealed in its original packaging.

What are the important precautions with Zanaflex?

Patients with liver dysfunction should use Zanaflex with caution due to increased risk of adverse effects. Regular health check-ups are recommended to monitor liver function during treatment.

Can I drive while taking Zanaflex?

Zanaflex may cause drowsiness or dizziness, thus, it's advisable to avoid driving or operating heavy machinery until you know how the medication affects you.

Zanaflex Ordering Information

Can I order Zanaflex online in UAE?

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Can I legally buy Zanaflex in UAE without a prescription?

One can legally order Zanaflex online in UAE via overseas online pharmacy. The order is legal as it originates from outside UAE and is subject to the laws of the country where it is sold.

Where can I safely purchase Zanaflex online in UAE?

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