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Carbidopa

Carbidopa, found in Sinemet and Stalevo, is used alongside levodopa for movement symptoms of Parkinson’s disease. This catalogue lists these two combination tablets.

Sinemet

Parkinson's Disease, Parkinsonism

100mg + 10mg · 100mg + 25mg · 250mg + 25mg

Carbidopa and levodopa tablets for Parkinson's disease. Levodopa becomes dopamine in the brain; carbidopa stops it breaking down in the body.

From$1.05/ tabletView

Stalevo

Parkinson's Disease

200mg + 100mg + 25mg

Levodopa, carbidopa and entacapone tablets for Parkinson's disease. The combination extends the effect of levodopa by slowing its breakdown.

From$0.85/ tabletView

Key points

  • Carbidopa is a decarboxylase inhibitor that reduces levodopa breakdown before it reaches the brain.
  • This can allow levodopa to address dopamine-related movement symptoms with less nausea and vomiting outside the brain.
  • Stopping suddenly can cause a serious syndrome with fever, rigidity, unusual movements and confusion.

Brands and forms in this catalogue

Both entries are tablets in Neurology. Sinemet contains carbidopa and levodopa, while Stalevo also contains entacapone. They are listed for Parkinson’s Disease, and Sinemet is also listed for Parkinsonism.

Further reading