Sinemet
Indicated to address motor coordination deficits to manage parkinsonian tremors and alleviate muscular rigidity.
- Category
- Neurology
- Route
- Oral use
- Form
- Tablet
- Strengths
- 100mg + 10mg · 100mg + 25mg · 250mg + 25mg
You will receive a quality generic equivalent of Sinemet, depending on stock.
Prescription and consultation requirements for Sinemet vary by destination and are determined by the fulfilment partner.
Sinemet details
- Conditions
- Parkinson's Disease · Parkinsonism
- Alternative names
- carbidopa, levodopa
- Therapeutic class
- Decarboxylase Inhibitor, Dopamine Precursor Combination
- Pharmacological class
- Antiparkinsonian Agent
- Known off-label uses
- restless legs syndrome
- Contraindications
- narrow-angle glaucoma; concurrent MAO inhibitors; history of melanoma
- Minor side effects
- nausea; dizziness; headache
- Moderate side effects
- dyskinesias; orthostatic hypotension; vivid dreams
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Merck
- Onset Time
- 30–60 minutes
- Duration
- 4–6 hours
- Storage instructions
- Store below 25°C. Protect from light.
- Drug interactions
- MAO Inhibitors; Iron Supplements; Haloperidol
- Age restrictions
- Approved for adults.
Serious side effects
severe hallucinations, requires immediate medical attention; neuroleptic malignant syndrome, requires immediate medical attention
Patient summary
indicated to address motor coordination deficits to manage parkinsonian tremors and alleviate muscular rigidity.
Mechanism of action
Levodopa converts to dopamine centrally, while carbidopa blocks peripheral conversion to minimise systemic side effects.
Pregnancy and breastfeeding
TGA Category C: Use if potential benefits exceed risks. Breastfeeding: May suppress lactation.
What you will receive
Sinemet is the originator brand name, made by Merck. We use it to identify the medicine and are not affiliated with Merck.
- The fulfilment partner confirms whether the exact brand or an equivalent containing Carbidopa / Levodopa is offered.
- The offered brand, manufacturer and dispatch location depend on the product, destination and partner warehouse.
- Check the final product details at checkout before confirming an order.