Sinemet
Carbidopa and levodopa tablets for Parkinson's disease. Levodopa becomes dopamine in the brain; carbidopa stops it breaking down in the body.
- Category
- Neurology
- Route
- Oral use
- Form
- Tablet
- Strengths
- 100mg + 10mg · 100mg + 25mg · 250mg + 25mg
This listing uses Sinemet as a reference name. A generic equivalent is supplied; its exact brand and manufacturer are confirmed before supply.
Prescription and consultation requirements for Sinemet vary by destination and are determined by the fulfilment partner.
Sinemet details
- Conditions
- Parkinson's Disease · Parkinsonism
- Alternative names
- carbidopa, levodopa
- Therapeutic class
- Decarboxylase Inhibitor, Dopamine Precursor Combination
- Pharmacological class
- Antiparkinsonian Agent
- Known off-label uses
- restless legs syndrome
- Contraindications
- narrow-angle glaucoma; concurrent MAO inhibitors; history of melanoma
- Minor side effects
- nausea; dizziness; headache
- Moderate side effects
- dyskinesias; orthostatic hypotension; vivid dreams
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Merck
- Onset Time
- 30–60 minutes
- Duration
- 4–6 hours
- Storage instructions
- Store below 25°C. Protect from light.
- Drug interactions
- MAO Inhibitors; Iron Supplements; Haloperidol
- Age restrictions
- Approved for adults.
Serious side effects
severe hallucinations, requires immediate medical attention; neuroleptic malignant syndrome, requires immediate medical attention
Patient summary
Carbidopa and levodopa tablets for Parkinson's disease. Levodopa becomes dopamine in the brain; carbidopa stops it breaking down in the body.
Mechanism of action
Levodopa converts to dopamine centrally, while carbidopa blocks peripheral conversion to minimise systemic side effects.
Pregnancy and breastfeeding
Pregnancy: Use if potential benefits exceed risks. Breastfeeding: May suppress lactation.
What you will receive
Sinemet is used here as a reference originator brand name to identify the medicine. We are not affiliated with the brand owner, and this listing does not offer the originator product.
- The supplied product is a generic equivalent containing Carbidopa / Levodopa, not the originator brand shown as the reference.
- The exact generic brand, manufacturer and dispatch location are confirmed based on the product, destination and available manufacturer or partner warehouse.
- Check the final product details at checkout before confirming an order.