Pioglitazone
Pioglitazone (Actos) is a medicine used with diet and exercise to improve blood glucose control in adults with type 2 diabetes. This listing includes Actos and Actoplus Met tablets.

Actoplus Met
Type 2 Diabetes Mellitus
15mg + 500mg
Pioglitazone and metformin tablets for type 2 diabetes. The two ingredients work on different aspects of blood sugar control.
Key points
- A boxed warning says pioglitazone can cause or worsen heart failure in some people.
- The CYP2C8 enzyme has the main role in how the liver processes pioglitazone.
- Actos contains pioglitazone alone, while Actoplus Met contains pioglitazone with metformin.
What Pioglitazone is used for
Pioglitazone hydrochloride, the ingredient in ACTOS, is used with diet and exercise to improve blood glucose control in adults with Type 2 Diabetes Mellitus. It changes how the body responds to insulin, lowering insulin resistance in the liver, fat and muscle. It is listed in Diabetes Management and is not effective for type 1 diabetes or diabetic ketoacidosis.
Further reading
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