Tolvaptan
Tolvaptan (Samsca) is a vasopressin receptor antagonist used to treat low sodium levels in the blood. This page covers the one formulation listed in the catalogue, Samsca.
Key points
- Tolvaptan is a vasopressin receptor antagonist that targets the hormone pathway controlling water balance in the body.
- It is listed for hypervolaemic hyponatraemia and euvolaemic hyponatraemia, two conditions where blood sodium drops to unsafe levels.
- The sole listed product is Samsca, a 15 mg tablet from Otsuka Pharmaceutical.
What Tolvaptan is used for
Tolvaptan is used to treat hyponatraemia, a condition where the body retains too much water and sodium becomes dangerously diluted. Hypervolaemic Hyponatraemia Euvolaemic Hyponatraemia As a Hormone Therapy medicine, tolvaptan acts on the kidneys to release extra water as dilute urine, raising sodium concentration in the blood.