Samsca
Tolvaptan tablets for low sodium levels in the body. It makes the kidneys pass extra water without flushing out sodium.
- Category
- Hormone Therapy
- Active ingredient
- Tolvaptan
- Route
- Oral use
- Form
- Tablet
- Strengths
- 15mg
This listing uses Samsca as a reference name. A generic equivalent is supplied; its exact brand and manufacturer are confirmed before supply.
Prescription and consultation requirements for Samsca vary by destination and are determined by the fulfilment partner.
Samsca details
- Conditions
- Hypervolaemic Hyponatraemia · Euvolaemic Hyponatraemia
- Alternative names
- tolvaptan
- Therapeutic class
- Selective Vasopressin V2 Receptor Antagonist
- Pharmacological class
- Vasopressin Antagonist
- Known off-label uses
- autosomal dominant polycystic kidney disease
- Minor side effects
- dry mouth; thirst; polyuria
- Moderate side effects
- pollakiuria; hyperglycaemia; constipation
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Otsuka Pharmaceutical
- Onset Time
- 2–4 hours
- Duration
- 24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Ketoconazole; Clarithromycin; Grapefruit
- Age restrictions
- Approved for adults.
- Pregnancy and breastfeeding
- Pregnancy: Use if potential benefits outweigh risks. Breastfeeding: Avoid.
Contraindications
urgent need to raise serum sodium; inability to sense or respond to thirst; hypovolaemic hyponatraemia
Serious side effects
osmotic demyelination syndrome, requires immediate medical attention; severe hepatotoxicity, requires immediate medical attention
Patient summary
Tolvaptan tablets for low sodium levels in the body. It makes the kidneys pass extra water without flushing out sodium.
Mechanism of action
Antagonises renal V2 receptors, preventing water reabsorption to promote excretion of free water without electrolyte loss.
What you will receive
Samsca is used here as a reference originator brand name to identify the medicine. We are not affiliated with the brand owner, and this listing does not offer the originator product.
- The supplied product is a generic equivalent containing Tolvaptan, not the originator brand shown as the reference.
- The exact generic brand, manufacturer and dispatch location are confirmed based on the product, destination and available manufacturer or partner warehouse.
- Check the final product details at checkout before confirming an order.