Voriconazole
Voriconazole (Vfend) is a triazole antifungal used for invasive aspergillosis and serious Candida infections. This listing includes Vfend tablets.
Key points
- Visual changes such as blurred vision, altered colour vision or sensitivity to light occurred in around 21% of people in therapeutic trials.
- Liver safety is important because serious liver reactions, including rare fatal cases, have occurred during treatment.
- Pregnancy exposure can cause harm to a developing baby.
How Voriconazole works
Voriconazole is a triazole antifungal that blocks a fungal enzyme needed to make ergosterol, a building block of the fungal cell membrane. Lower ergosterol levels can stop the fungus from maintaining its cell membrane.
Further reading
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