Vfend
Developed to target serious fungal infections, this medication is indicated to address invasive aspergillosis and is utilised in systemic treatment protocols.
- Category
- Antifungals
- Active ingredient
- Voriconazole
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 200mg
You will receive a quality generic equivalent of Vfend, depending on stock.
Prescription and consultation requirements for Vfend vary by destination and are determined by the fulfilment partner.
Vfend details
- Conditions
- Invasive Aspergillosis · Candidaemia · Oesophageal Candidiasis
- Therapeutic class
- Triazole Antifungal
- Pharmacological class
- Antifungal
- Precautions and warnings
- avoid prolonged sun exposure; monitor liver function; monitor visual function
- Minor side effects
- visual disturbances; nausea; vomiting; rash
- Moderate side effects
- elevated liver enzymes; peripheral oedema; headache
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Pfizer
- Onset Time
- 1–2 hours
- Duration
- 12 hours
- Storage instructions
- Store at room temperature.
- Drug interactions
- rifampicin; carbamazepine; pimozide; quinidine
- Age restrictions
- Use with caution in paediatric patients.
Contraindications
hypersensitivity to voriconazole; concurrent use of rifampicin; concurrent use of carbamazepine
Serious side effects
hepatotoxicity, requires immediate medical attention; photosensitivity, requires immediate medical attention; qt prolongation, requires immediate medical attention
Patient summary
Developed to target serious fungal infections, this medication is indicated to address invasive aspergillosis and is utilised in systemic treatment protocols.
Mechanism of action
Voriconazole inhibits fungal cytochrome P450-dependent 14-alpha-sterol demethylase, which is vital for fungal ergosterol biosynthesis, effectively disrupting fungal cell membrane formation.
Pregnancy and breastfeeding
Pregnancy: Use is not recommended unless clearly necessary. Breastfeeding: Discontinue breastfeeding during treatment.
What you will receive
Vfend is the originator brand name, made by Pfizer. We use it to identify the medicine and are not affiliated with Pfizer.
- The fulfilment partner confirms whether the exact brand or an equivalent containing Voriconazole is offered.
- The offered brand, manufacturer and dispatch location depend on the product, destination and partner warehouse.
- Check the final product details at checkout before confirming an order.