Vfend
Voriconazole tablets for invasive aspergillosis and systemic candidiasis. It disrupts fungal cell membranes to stop the infection.
- Category
- Antifungals
- Active ingredient
- Voriconazole
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 200mg
This listing uses Vfend as a reference name. A generic equivalent is supplied; its exact brand and manufacturer are confirmed before supply.
Prescription and consultation requirements for Vfend vary by destination and are determined by the fulfilment partner.
Vfend details
- Therapeutic class
- Triazole Antifungal
- Pharmacological class
- Antifungal
- Precautions and warnings
- avoid prolonged sun exposure; monitor liver function; monitor visual function
- Minor side effects
- visual disturbances; nausea; vomiting; rash
- Moderate side effects
- elevated liver enzymes; peripheral oedema; headache
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Pfizer
- Onset Time
- 1–2 hours
- Duration
- 12 hours
- Storage instructions
- Store at room temperature.
- Drug interactions
- rifampicin; carbamazepine; pimozide; quinidine
- Age restrictions
- Use with caution in paediatric patients.
Contraindications
hypersensitivity to voriconazole; concurrent use of rifampicin; concurrent use of carbamazepine
Serious side effects
hepatotoxicity, requires immediate medical attention; photosensitivity, requires immediate medical attention; qt prolongation, requires immediate medical attention
Patient summary
Voriconazole tablets for invasive aspergillosis and systemic candidiasis. It disrupts fungal cell membranes to stop the infection.
Mechanism of action
Voriconazole inhibits fungal cytochrome P450-dependent 14-alpha-sterol demethylase, which is vital for fungal ergosterol biosynthesis, effectively disrupting fungal cell membrane formation.
Pregnancy and breastfeeding
Pregnancy: Use is not recommended unless clearly necessary. Breastfeeding: Discontinue breastfeeding during treatment.
What you will receive
Vfend is used here as a reference originator brand name to identify the medicine. We are not affiliated with the brand owner, and this listing does not offer the originator product.
- The supplied product is a generic equivalent containing Voriconazole, not the originator brand shown as the reference.
- The exact generic brand, manufacturer and dispatch location are confirmed based on the product, destination and available manufacturer or partner warehouse.
- Check the final product details at checkout before confirming an order.