Clozaril
Indicated to address treatment-resistant schizophrenia to relieve severe psychiatric symptoms and support mental stabilisation.
- Category
- Mental Health
- Active ingredient
- Clozapine
- Route
- Oral use
- Form
- Tablet
- Strengths
- 50mg · 100mg
You will receive a quality generic equivalent of Clozaril, depending on stock.
Prescription and consultation requirements for Clozaril vary by destination and are determined by the fulfilment partner.
Clozaril details
- Condition
- Treatment-resistant Schizophrenia
- Alternative names
- clozapine
- Therapeutic class
- Second-Generation Antipsychotic
- Pharmacological class
- Atypical Antipsychotic
- Known off-label uses
- suicidal behaviour in schizophrenia
- Minor side effects
- somnolence; dizziness; sialorrhoea
- Moderate side effects
- tachycardia; weight gain; constipation
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Novartis
- Onset Time
- 1–2 weeks
- Duration
- 24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Alcohol; Benzodiazepines; Ciprofloxacin
- Age restrictions
- Approved for adults over eighteen years.
Contraindications
history of drug-induced agranulocytosis; severe bone marrow disorders; uncontrolled epilepsy
Serious side effects
agranulocytosis, requires immediate medical attention; myocarditis, requires immediate medical attention; seizures, requires immediate medical attention
Patient summary
indicated to address treatment-resistant schizophrenia to relieve severe psychiatric symptoms and support mental stabilisation.
Mechanism of action
Antagonises dopamine D2 and serotonin 5-HT2A receptors with high affinity, normalising hyperactive central pathways without producing extrapyramidal dominance.
Pregnancy and breastfeeding
TGA Category B: Safety established in animal studies. Breastfeeding: Contraindicated.
What you will receive
Clozaril is the originator brand name, made by Novartis. We use it to identify the medicine and are not affiliated with Novartis.
- The fulfilment partner confirms whether the exact brand or an equivalent containing Clozapine is offered.
- The offered brand, manufacturer and dispatch location depend on the product, destination and partner warehouse.
- Check the final product details at checkout before confirming an order.