Clozaril
Clozapine tablets for treatment-resistant schizophrenia. It acts on both dopamine and serotonin receptors, and is used when other antipsychotics have not worked.
- Category
- Mental Health
- Active ingredient
- Clozapine
- Route
- Oral use
- Form
- Tablet
- Strengths
- 50mg · 100mg
This listing uses Clozaril as a reference name. A generic equivalent is supplied; its exact brand and manufacturer are confirmed before supply.
Prescription and consultation requirements for Clozaril vary by destination and are determined by the fulfilment partner.
Clozaril details
- Condition
- Treatment-resistant Schizophrenia
- Alternative names
- clozapine
- Therapeutic class
- Second-Generation Antipsychotic
- Pharmacological class
- Atypical Antipsychotic
- Known off-label uses
- suicidal behaviour in schizophrenia
- Minor side effects
- somnolence; dizziness; sialorrhoea
- Moderate side effects
- tachycardia; weight gain; constipation
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Novartis
- Onset Time
- 1–2 weeks
- Duration
- 24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Alcohol; Benzodiazepines; Ciprofloxacin
- Age restrictions
- Approved for adults over eighteen years.
Contraindications
history of drug-induced agranulocytosis; severe bone marrow disorders; uncontrolled epilepsy
Serious side effects
agranulocytosis, requires immediate medical attention; myocarditis, requires immediate medical attention; seizures, requires immediate medical attention
Patient summary
Clozapine tablets for treatment-resistant schizophrenia. It acts on both dopamine and serotonin receptors, and is used when other antipsychotics have not worked.
Mechanism of action
Antagonises dopamine D2 and serotonin 5-HT2A receptors with high affinity, normalising hyperactive central pathways without producing extrapyramidal dominance.
Pregnancy and breastfeeding
Pregnancy: Suitability during pregnancy depends on the specific medicine and individual circumstances. Confirm with a qualified clinician or pharmacist before use. Breastfeeding: Contraindicated.
What you will receive
Clozaril is used here as a reference originator brand name to identify the medicine. We are not affiliated with the brand owner, and this listing does not offer the originator product.
- The supplied product is a generic equivalent containing Clozapine, not the originator brand shown as the reference.
- The exact generic brand, manufacturer and dispatch location are confirmed based on the product, destination and available manufacturer or partner warehouse.
- Check the final product details at checkout before confirming an order.