Kaletra
A lopinavir and ritonavir tablet for HIV-1 infection. Ritonavir prolongs the effect of lopinavir, so the two are paired.
- Categories
- HIV Management · Antivirals
- Route
- Oral use
- Form
- Tablet
- Strengths
- 200mg + 50mg
This listing uses Kaletra as a reference name. A generic equivalent is supplied; its exact brand and manufacturer are confirmed before supply.
Prescription and consultation requirements for Kaletra vary by destination and are determined by the fulfilment partner.
Kaletra details
- Alternative names
- lopinavir, ritonavir
- Therapeutic class
- HIV Protease Inhibitor Combination
- Pharmacological class
- Antiretroviral Combination
- Contraindications
- concurrent use of highly CYP3A-dependent drugs; severe hepatic impairment
- Minor side effects
- diarrhoea; nausea; headache
- Moderate side effects
- hyperlipidaemia; vomiting; abdominal pain
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- AbbVie
- Onset Time
- 2–4 weeks
- Duration
- 12 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Rifampin; Simvastatin; St. John's Wort
- Age restrictions
- Approved for paediatric patients over fourteen days of age and adults.
Serious side effects
severe pancreatitis, requires immediate medical attention; QT prolongation, requires immediate medical attention; hepatotoxicity, requires immediate medical attention
Patient summary
A lopinavir and ritonavir tablet for HIV-1 infection. Ritonavir prolongs the effect of lopinavir, so the two are paired.
Mechanism of action
Lopinavir blocks the HIV protease enzyme, preventing cleavage of polyproteins, while ritonavir acts as a pharmacokinetic enhancer.
Pregnancy and breastfeeding
Pregnancy: Suitability during pregnancy depends on the specific medicine and individual circumstances. Confirm with a qualified clinician or pharmacist before use. Breastfeeding: Not recommended in HIV-positive patients.
What you will receive
Kaletra is used here as a reference originator brand name to identify the medicine. We are not affiliated with the brand owner, and this listing does not offer the originator product.
- The supplied product is a generic equivalent containing Lopinavir / Ritonavir, not the originator brand shown as the reference.
- The exact generic brand, manufacturer and dispatch location are confirmed based on the product, destination and available manufacturer or partner warehouse.
- Check the final product details at checkout before confirming an order.