Motegrity

Designed to support colonic motility to manage chronic constipation and alleviate abdominal fullness.

Dosage

Pack size

You will receive a quality generic equivalent of Motegrity, depending on stock.

Prescription and consultation requirements for Motegrity vary by destination and are determined by the fulfilment partner.

Motegrity details

Condition: Chronic Idiopathic Constipation
Alternative names: prucalopride
Therapeutic class: Selective 5-HT4 Receptor Agonist
Pharmacological class: Prokinetic Agent
Minor side effects: headache; nausea; diarrhoea
Moderate side effects: abdominal pain; decreased appetite; fatigue
Serious side effects: severe depression and suicidal ideation, requires immediate medical attention
Dosage forms: Tablet
Administration route: Oral use
Supply category: Prescription-only medicine (POM)
Originator: Shire
Onset Time: 24–48 hours
Duration: 24 hours
Storage instructions: Store below 25°C.
Drug interactions: Erythromycin; Ketoconazole
Age restrictions: Approved for adults.

Contraindications

renal impairment requiring dialysis; intestinal perforation; obstructive bowel disorders

Patient summary

designed to support colonic motility to manage chronic constipation and alleviate abdominal fullness.

Mechanism of action

Stimulates 5-HT4 receptors in gut walls, enhancing peristaltic contractions to optimise bowel movement frequency.

Pregnancy and breastfeeding

TGA Category C: Limited clinical records. Avoid in pregnancy. Breastfeeding: Expelled in low amounts.

Motegrity is the originator brand name, made by Shire. We use it to identify the medicine and are not affiliated with Shire.

The fulfilment partner confirms whether the exact brand or an equivalent containing Prucalopride is offered.
The offered brand, manufacturer and dispatch location depend on the product, destination and partner warehouse.
Check the final product details at checkout before confirming an order.