
Motegrity
Prucalopride tablets for chronic constipation. It stimulates the bowel's own nerves to get things moving again.
- Category
- Digestive Health
- Active ingredient
- Prucalopride
- Route
- Oral use
- Form
- Tablet
- Strengths
- 1mg · 2mg
This listing uses Motegrity as a reference name. A generic equivalent is supplied; its exact brand and manufacturer are confirmed before supply.
Prescription and consultation requirements for Motegrity vary by destination and are determined by the fulfilment partner.
Motegrity details
- Condition
- Chronic Idiopathic Constipation
- Alternative names
- prucalopride
- Therapeutic class
- Selective 5-HT4 Receptor Agonist
- Pharmacological class
- Prokinetic Agent
- Minor side effects
- headache; nausea; diarrhoea
- Moderate side effects
- abdominal pain; decreased appetite; fatigue
- Serious side effects
- severe depression and suicidal ideation, requires immediate medical attention
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Shire
- Onset Time
- 24–48 hours
- Duration
- 24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Erythromycin; Ketoconazole
- Age restrictions
- Approved for adults.
Contraindications
renal impairment requiring dialysis; intestinal perforation; obstructive bowel disorders
Patient summary
Prucalopride tablets for chronic constipation. It stimulates the bowel's own nerves to get things moving again.
Mechanism of action
Stimulates 5-HT4 receptors in gut walls, enhancing peristaltic contractions to optimise bowel movement frequency.
Pregnancy and breastfeeding
Pregnancy: Limited clinical records. Avoid in pregnancy. Breastfeeding: Expelled in low amounts.
What you will receive
Motegrity is used here as a reference originator brand name to identify the medicine. We are not affiliated with the brand owner, and this listing does not offer the originator product.
- The supplied product is a generic equivalent containing Prucalopride, not the originator brand shown as the reference.
- The exact generic brand, manufacturer and dispatch location are confirmed based on the product, destination and available manufacturer or partner warehouse.
- Check the final product details at checkout before confirming an order.