Skip to content
Motegrity

Motegrity

Prucalopride

Prucalopride tablets for chronic constipation. It stimulates the bowel's own nerves to get things moving again.

Active ingredient
Prucalopride
Route
Oral use
Form
Tablet
Strengths
1mg · 2mg

This listing uses Motegrity as a reference name. A generic equivalent is supplied; its exact brand and manufacturer are confirmed before supply.

Prescription and consultation requirements for Motegrity vary by destination and are determined by the fulfilment partner.

Motegrity details

Alternative names
prucalopride
Therapeutic class
Selective 5-HT4 Receptor Agonist
Pharmacological class
Prokinetic Agent
Minor side effects
headache; nausea; diarrhoea
Moderate side effects
abdominal pain; decreased appetite; fatigue
Serious side effects
severe depression and suicidal ideation, requires immediate medical attention
Dosage forms
Tablet
Administration route
Oral use
Supply category
Prescription-only medicine (POM)
Originator
Shire
Onset Time
24–48 hours
Duration
24 hours
Storage instructions
Store below 25°C.
Drug interactions
Erythromycin; Ketoconazole
Age restrictions
Approved for adults.
Contraindications

renal impairment requiring dialysis; intestinal perforation; obstructive bowel disorders

Patient summary

Prucalopride tablets for chronic constipation. It stimulates the bowel's own nerves to get things moving again.

Mechanism of action

Stimulates 5-HT4 receptors in gut walls, enhancing peristaltic contractions to optimise bowel movement frequency.

Pregnancy and breastfeeding

Pregnancy: Limited clinical records. Avoid in pregnancy. Breastfeeding: Expelled in low amounts.

What you will receive

Motegrity is used here as a reference originator brand name to identify the medicine. We are not affiliated with the brand owner, and this listing does not offer the originator product.

  • The supplied product is a generic equivalent containing Prucalopride, not the originator brand shown as the reference.
  • The exact generic brand, manufacturer and dispatch location are confirmed based on the product, destination and available manufacturer or partner warehouse.
  • Check the final product details at checkout before confirming an order.

How we compare medicine brands and generics