Valparin
Valproic acid tablets for seizures and bipolar mania. It raises GABA levels to calm overactive nerve signals.
- Category
- Mental Health
- Active ingredient
- Valproic Acid
- Route
- Oral use
- Form
- Tablet
- Strengths
- 250mg · 500mg · 750mg
Prescription and consultation requirements for Valparin vary by destination and are determined by the fulfilment partner.
Valparin details
- Conditions
- Seizure Disorders · Bipolar Manic Episodes
- Alternative names
- valproate
- Therapeutic class
- Anticonvulsant
- Pharmacological class
- Antiepileptic Agent
- Known off-label uses
- migraine prophylaxis
- Minor side effects
- nausea; somnolence; dizziness
- Moderate side effects
- weight gain; thrombocytopenia; alopecia
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Manufacturer
- Sanofi-Aventis
- Onset Time
- 1–2 weeks
- Duration
- 12–24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Aspirin; Lamotrigine; Carbamazepine
- Age restrictions
- Approved for children, adolescents, and adults.
Contraindications
active hepatic disease; mitochondrial disorders (POLG mutation); pregnancy (for migraine prophylaxis)
Serious side effects
severe hepatotoxicity, requires immediate medical attention; acute pancreatitis, requires immediate medical attention; suicidal ideation, requires immediate medical attention
Patient summary
Valproic acid tablets for seizures and bipolar mania. It raises GABA levels to calm overactive nerve signals.
Mechanism of action
Increases GABA concentration in brain synapses, blocking repetitive high-frequency neuronal firing and reducing excitability.
Pregnancy and breastfeeding
Pregnancy: High risk of congenital malformations and cognitive impairment. Avoid in pregnancy. Breastfeeding: Caution advised.