Depakote
Divalproex tablets for seizures and bipolar mania. They calm excessive brain activity that triggers these episodes.
- Category
- Neurology
- Active ingredient
- Divalproex
- Route
- Oral use
- Form
- Tablet
- Strengths
- 125mg · 250mg · 500mg · 750mg
This listing uses Depakote as a reference name. A generic equivalent is supplied; its exact brand and manufacturer are confirmed before supply.
Prescription and consultation requirements for Depakote vary by destination and are determined by the fulfilment partner.
Depakote details
- Alternative names
- divalproex sodium
- Therapeutic class
- Histone Deacetylase Inhibitor
- Pharmacological class
- Anticonvulsant
- Minor side effects
- nausea; somnolence; dizziness
- Moderate side effects
- weight gain; thrombocytopenia; alopecia
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- AbbVie
- Onset Time
- 1–2 weeks
- Duration
- 12–24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Aspirin; Lamotrigine; Carbamazepine
- Age restrictions
- Approved for children over two years, adolescents, and adults.
Contraindications
active hepatic disease; mitochondrial disorders (POLG mutation); pregnancy (for migraine prophylaxis)
Serious side effects
severe hepatotoxicity, requires immediate medical attention; acute pancreatitis, requires immediate medical attention; suicidal ideation, requires immediate medical attention
Patient summary
Divalproex tablets for seizures and bipolar mania. They calm excessive brain activity that triggers these episodes.
Mechanism of action
Enhances GABA neurotransmitter levels in cerebral synapses, blocking high-frequency neuronal firing and reducing cellular hyperexcitability.
Pregnancy and breastfeeding
Pregnancy: High risk of congenital malformations and developmental delay. Contraindicated for migraine prevention. Breastfeeding: Caution advised.
What you will receive
Depakote is used here as a reference originator brand name to identify the medicine. We are not affiliated with the brand owner, and this listing does not offer the originator product.
- The supplied product is a generic equivalent containing Divalproex, not the originator brand shown as the reference.
- The exact generic brand, manufacturer and dispatch location are confirmed based on the product, destination and available manufacturer or partner warehouse.
- Check the final product details at checkout before confirming an order.