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Depakote

Divalproex

Formulated to alleviate neural hyperarousal to support seizure threshold management and target bipolar mood swings.

Category
Neurology
Active ingredient
Divalproex
Route
Oral use
Form
Tablet
Strengths
125mg · 250mg · 500mg · 750mg

You will receive a quality generic equivalent of Depakote, depending on stock.

Prescription and consultation requirements for Depakote vary by destination and are determined by the fulfilment partner.

Depakote details

Alternative names
divalproex sodium
Therapeutic class
Histone Deacetylase Inhibitor
Pharmacological class
Anticonvulsant
Minor side effects
nausea; somnolence; dizziness
Moderate side effects
weight gain; thrombocytopenia; alopecia
Dosage forms
Tablet
Administration route
Oral use
Supply category
Prescription-only medicine (POM)
Originator
AbbVie
Onset Time
1–2 weeks
Duration
12–24 hours
Storage instructions
Store below 25°C.
Drug interactions
Aspirin; Lamotrigine; Carbamazepine
Age restrictions
Approved for children over two years, adolescents, and adults.
Contraindications

active hepatic disease; mitochondrial disorders (POLG mutation); pregnancy (for migraine prophylaxis)

Serious side effects

severe hepatotoxicity, requires immediate medical attention; acute pancreatitis, requires immediate medical attention; suicidal ideation, requires immediate medical attention

Patient summary

formulated to alleviate neural hyperarousal to support seizure threshold management and target bipolar mood swings.

Mechanism of action

Enhances GABA neurotransmitter levels in cerebral synapses, blocking high-frequency neuronal firing and reducing cellular hyperexcitability.

Pregnancy and breastfeeding

TGA Category D/X: High risk of congenital malformations and developmental delay. Contraindicated for migraine prevention. Breastfeeding: Caution advised.

What you will receive

Depakote is the originator brand name, made by AbbVie. We use it to identify the medicine and are not affiliated with AbbVie.

  • The fulfilment partner confirms whether the exact brand or an equivalent containing Divalproex is offered.
  • The offered brand, manufacturer and dispatch location depend on the product, destination and partner warehouse.
  • Check the final product details at checkout before confirming an order.

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