Skip to content

Amitriptyline

Amitriptyline (Endep) is a tricyclic antidepressant listed for relief of depression symptoms. This catalogue includes Endep and Elavil, both tablet brands with the same listed strengths.

Endep

Major Depressive Disorder, Neuropathic Pain

10mg · 25mg · 50mg · 75mg

Amitriptyline tablets for depression and nerve pain. They are often given at a lower dose for pain than for mood.

From$0.46/ tabletView

Elavil

Major Depressive Disorder

10mg · 25mg · 50mg · 75mg

Amitriptyline tablets for major depressive disorder. They belong to an older class of antidepressants that can also be sedating.

From$0.60/ tabletView

Key points

  • CYP2D6 activity is lower in some people, who can reach higher than expected amitriptyline concentrations in their blood.
  • The boxed warning identifies suicidal thinking and behaviour as a risk in children, adolescents and young adults taking antidepressants.
  • A syndrome resembling neuroleptic malignant syndrome has very rarely been reported after amitriptyline treatment began or the dose was increased.

Uses and tablet brands

The label describes amitriptyline for relief of depression symptoms. MedlinePlus also lists post-herpetic neuralgia, nerve pain that can continue after a shingles infection. In this catalogue it is listed for Major Depressive Disorder and Neuropathic Pain. Endep and Elavil contain amitriptyline alone as tablets, with the same four listed strengths.

Further reading

Related articles