Endep
Utilised to manage chronic depressive symptoms to alleviate emotional distress and support synaptic monoamine stability.
- Category
- Antidepressants
- Active ingredient
- Amitriptyline
- Route
- Oral use
- Form
- Tablet
- Strengths
- 10mg · 25mg · 50mg · 75mg
You will receive a quality generic equivalent of Endep, depending on stock.
Prescription and consultation requirements for Endep vary by destination and are determined by the fulfilment partner.
Endep details
- Conditions
- Major Depressive Disorder · Neuropathic Pain
- Alternative names
- amitriptyline
- Therapeutic class
- Tricyclic Antidepressant (TCA)
- Pharmacological class
- Antidepressant
- Known off-label uses
- migraine prophylaxis
- Minor side effects
- dry mouth; drowsiness; constipation
- Moderate side effects
- blurred vision; weight gain; orthostatic hypotension
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Alphapharm
- Onset Time
- 1–4 weeks
- Duration
- 24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- MAO Inhibitors; Alcohol; QT-prolonging drugs
- Age restrictions
- Approved for children over twelve years, adolescents, and adults.
Contraindications
recent myocardial infarction; concurrent use of MAO inhibitors; severe liver disease
Serious side effects
suicidal ideation, requires immediate medical attention; serotonin syndrome, requires immediate medical attention
Patient summary
utilised to manage chronic depressive symptoms to alleviate emotional distress and support synaptic monoamine stability.
Mechanism of action
Blocks presynaptic reuptake transporters for serotonin and norepinephrine, enhancing central neurotransmission and blocking nociception.
Pregnancy and breastfeeding
TGA Category C: Use if potential benefit outweighs risk. Breastfeeding: Expelled in low quantities.
What you will receive
Endep is the originator brand name, made by Alphapharm. We use it to identify the medicine and are not affiliated with Alphapharm.
- The fulfilment partner confirms whether the exact brand or an equivalent containing Amitriptyline is offered.
- The offered brand, manufacturer and dispatch location depend on the product, destination and partner warehouse.
- Check the final product details at checkout before confirming an order.