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Amlodipine

Amlodipine (Norvasc) is a calcium channel blocker used to treat high blood pressure and chronic stable angina. This catalogue lists it as the single-ingredient Norvasc, and combined with other blood pressure medicines in Azor, Tribenzor and Exforge.

Norvasc

Hypertension, Coronary Artery Disease

2.5mg · 5mg · 10mg

Amlodipine tablets for high blood pressure and coronary artery disease. It widens arteries by blocking calcium entry, easing blood flow.

From$0.44/ tabletView

Azor

Hypertension

20mg + 5mg · 40mg + 5mg

Olmesartan medoxomil and amlodipine tablets for high blood pressure. One ingredient relaxes blood vessels while the other relaxes artery walls.

From$1.53/ tabletView

Tribenzor

Hypertension

20mg + 5mg + 12.5mg

Olmesartan and amlodipine tablets for high blood pressure. They combine two medicines that relax blood vessels in different ways.

From$1.74/ tabletView

Exforge

Hypertension

5mg + 80mg

Amlodipine and valsartan tablets for high blood pressure. Two medicines in one pill, each lowering pressure differently.

From$1.13/ tabletView

Key points

  • Amlodipine’s absolute bioavailability is estimated at 64 to 90%, with a terminal elimination half-life of around 30 to 50 hours.
  • Oedema is amlodipine’s most commonly reported side effect, showing up in a dose-related pattern: 10.8% of patients on the 10 mg dose against 0.6% on placebo.
  • Your liver processes about 90% of amlodipine into inactive substances, with the remainder passed largely unchanged in urine.

What Amlodipine is used for

Norvasc’s label states that amlodipine treats Hypertension, lowering blood pressure, and gives symptomatic relief from Chronic Stable Angina, regular chest pain that follows a predictable pattern. Azor, Tribenzor and Exforge use amlodipine as part of a combination for high blood pressure, pairing it with a second or third blood pressure medicine in one tablet.

Brands and forms in this catalogue

Norvasc lists amlodipine on its own, as a tablet in 2.5 mg, 5 mg and 10 mg strengths, and its originator is Pfizer. The other three brands combine amlodipine with a second or third blood pressure medicine in one tablet: Azor pairs it with olmesartan medoxomil, Tribenzor adds hydrochlorothiazide to that same pairing, and Exforge combines it with valsartan. Azor and Tribenzor were originated by Daiichi Sankyo, and Exforge by Novartis, which is why this single active ingredient carries different owning brands across the Heart & Blood Pressure category rather than one company covering the whole line. Norvasc is the amlodipine brand name a UAE shopper is most likely to already recognise.

Further reading

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