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Glipizide

Glipizide (Metaglip) is a sulfonylurea medicine for lowering blood glucose in adults with type 2 diabetes. This listing includes Glucotrol XL and Metaglip.

Glucotrol Xl

Type 2 Diabetes Mellitus

2.5mg · 5mg · 10mg

Glipizide extended-release tablets for type 2 diabetes. The prolonged release keeps the pancreas nudged to make insulin steadily, rather than in one short burst.

From$0.16/ tabletView

Metaglip

Type 2 Diabetes Mellitus

2.5mg + 500mg · 5mg + 500mg

Glipizide and metformin tablets for type 2 diabetes. One part stimulates the pancreas to make insulin, the other lessens sugar production in the liver.

From$0.47/ tabletView

Key points

  • Glucotrol XL contains glipizide alone, while Metaglip combines glipizide with metformin.
  • Hepatic processing is the main way glipizide is cleared, with less than 10% leaving the body unchanged in urine or faeces.
  • G6PD deficiency can raise the risk of haemolytic anaemia with glipizide or another sulfonylurea.

How glipizide works

For Type 2 Diabetes Mellitus, glipizide is used with diet and exercise to improve blood glucose control in adults. It is a sulfonylurea that prompts the pancreas to release insulin, an effect that depends on insulin-making cells continuing to work.

Further reading

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