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Hydrochlorothiazide

Hydrochlorothiazide is a thiazide diuretic, usually combined with another blood pressure medicine to treat hypertension by lowering blood pressure. This catalogue lists it across 11 medicines, including Micardis Hct, Diovan Hct and Hyzaar, and 8 more.

Micardis Hct

Hypertension

40mg + 12.5mg · 80mg + 12.5mg

Telmisartan and hydrochlorothiazide tablets for high blood pressure. One part relaxes blood vessels, the other removes extra fluid.

From$1.57/ tabletView

Diovan Hct

Hypertension

80mg + 12.5mg · 160mg + 12.5mg

Valsartan and hydrochlorothiazide tablets for high blood pressure. One part relaxes vessels, the other sheds extra fluid.

From$1.63/ tabletView

Hyzaar

Hypertension, Stroke Prevention

12.5mg + 12.5mg · 25mg + 12.5mg · 50mg + 12.5mg

Losartan and hydrochlorothiazide tablets for high blood pressure and stroke prevention. Losartan blocks a constricting hormone, the diuretic removes extra fluid.

From$0.51/ tabletView

Zestoretic

Hypertension

5mg + 12.5mg

Lisinopril and hydrochlorothiazide tablets for high blood pressure. The two ingredients lower it by different routes.

From$1.68/ tabletView

Ziac

Hypertension

5mg + 12.5mg

Bisoprolol and hydrochlorothiazide tablets for high blood pressure. One ingredient slows the heart, the other removes excess fluid.

From$1.46/ tabletView

Benicar Hct

Hypertension

40mg + 12.5mg

Olmesartan medoxomil and hydrochlorothiazide tablets for high blood pressure. One part relaxes blood vessels while the other helps the body flush out excess fluid.

From$1.56/ tabletView

Tribenzor

Hypertension

20mg + 5mg + 12.5mg

Olmesartan and amlodipine tablets for high blood pressure. They combine two medicines that relax blood vessels in different ways.

From$1.74/ tabletView

Hydrocl

Hypertension, Oedema

12.5mg · 25mg

Hydrochlorothiazide tablets for high blood pressure and oedema. A thiazide diuretic that lowers blood pressure by shedding excess fluid through the kidneys.

From$0.53/ tabletView

Moduretic

Hypertension, Oedema

5mg + 50mg

Amiloride and hydrochlorothiazide tablets for high blood pressure and swelling. It removes extra fluid while helping keep potassium.

From$0.55/ tabletView

Avalide

Hypertension

162.5mg

Irbesartan and hydrochlorothiazide tablets for high blood pressure. Two different types of blood pressure medicine combined in one tablet.

From$2.08/ tabletView

Vaseretic

Hypertension

10mg + 25mg

Enalapril and hydrochlorothiazide tablets for high blood pressure. One part relaxes blood vessels, the other removes excess fluid.

From$0.89/ tabletView

Key points

  • As a thiazide diuretic, hydrochlorothiazide can lower blood potassium and sodium levels, and it increases how much magnesium leaves in urine, which may lead to low magnesium levels.
  • Being a sulfonamide, it can cause an idiosyncratic reaction that brings on sudden blurred vision or eye pain from temporary short-sightedness and acute angle-closure glaucoma, usually within hours to weeks of starting it.
  • Hypersensitivity reactions can happen to anyone taking hydrochlorothiazide, though the label notes they’re more likely if you have a history of allergies or asthma.

What Hydrochlorothiazide is used for

Ten of the eleven medicines here pair hydrochlorothiazide with a second blood pressure treatment, such as an angiotensin receptor blocker or ACE inhibitor, that works on a different part of the system. That combination is what treats Hypertension, and because lowering blood pressure this way also cuts the risk of stroke and heart attack, Hyzaar’s combination is listed for Stroke Prevention as well.

Brands and forms in this catalogue

All 11 medicines here come as tablets, so what changes between them is strength and which second blood pressure medicine hydrochlorothiazide is paired with. Micardis Hct (with telmisartan), Diovan Hct (with valsartan) and Hyzaar (with losartan) are originator combinations from Boehringer Ingelheim, Novartis and Merck. Zestoretic, Ziac, Benicar Hct, Tribenzor, Moduretic, Avalide and Vaseretic are further originator combinations in this catalogue’s Heart & Blood Pressure category, pairing hydrochlorothiazide with lisinopril, bisoprolol, olmesartan, amiloride, irbesartan or enalapril. Hydrocl, made by Healing Pharma, is the catalogue’s only single-ingredient line, offering hydrochlorothiazide on its own rather than in combination, and is also listed for oedema alongside Moduretic.

Further reading

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