Hyzaar
Losartan · Hydrochlorothiazide
Indicated to address severe hypertension to relieve vascular strain and manage circulatory volume.
- Category
- Heart & Blood Pressure
- Active ingredients
- Losartan · Hydrochlorothiazide
- Route
- Oral use
- Form
- Tablet
- Strengths
- 12.5mg + 12.5mg · 25mg + 12.5mg · 50mg + 12.5mg
You will receive a quality generic equivalent of Hyzaar, depending on stock.
Prescription and consultation requirements for Hyzaar vary by destination and are determined by the fulfilment partner.
Hyzaar details
- Conditions
- Hypertension · Stroke Prevention
- Alternative names
- losartan, hydrochlorothiazide
- Therapeutic class
- Angiotensin II Receptor Antagonist, Thiazide Diuretic Combination
- Pharmacological class
- Antihypertensive Combination
- Contraindications
- pregnancy; anuria; severe renal impairment
- Minor side effects
- dizziness; headache; fatigue
- Moderate side effects
- hyperkalaemia; electrolyte depletion; hypotension
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Merck
- Onset Time
- 1–2 hours
- Duration
- 24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Lithium; NSAIDs; Potassium Supplements
- Age restrictions
- Approved for adults.
Serious side effects
angioedema, requires immediate medical attention; severe acute renal failure, requires immediate medical attention
Patient summary
indicated to address severe hypertension to relieve vascular strain and manage circulatory volume.
Mechanism of action
Losartan blocks vasoconstricting AT1 receptors, while hydrochlorothiazide clears excess sodium and water via the kidneys.
Pregnancy and breastfeeding
TGA Category D: High risk of fetal injury and death. Contraindicated in pregnancy. Breastfeeding: Not recommended.
What you will receive
Hyzaar is the originator brand name, made by Merck. We use it to identify the medicine and are not affiliated with Merck.
- The fulfilment partner confirms whether the exact brand or an equivalent containing Losartan / Hydrochlorothiazide is offered.
- The offered brand, manufacturer and dispatch location depend on the product, destination and partner warehouse.
- Check the final product details at checkout before confirming an order.