Differin
Indicated to address follicular keratinisation to relieve acne lesions and support clear skin surfaces.
Differin details
- Condition
- Acne Vulgaris
- Alternative names
- adapalene
- Therapeutic class
- Third-Generation Topical Retinoid
- Pharmacological class
- Retinoid
- Known off-label uses
- rosacea
- Contraindications
- hypersensitivity to adapalene; broken or eczematous skin
- Minor side effects
- skin dryness; erythema; skin scaling
- Moderate side effects
- burning sensation; pruritus; sun sensitivity
- Serious side effects
- severe localised angioedema, requires immediate medical attention
- Dosage forms
- Cream
- Administration route
- Cutaneous use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Galderma
- Onset Time
- 2–4 weeks
- Duration
- 24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Benzoyl Peroxide; Salicylic Acid
- Age restrictions
- Approved for paediatric patients over twelve years and adults.
Patient summary
indicated to address follicular keratinisation to relieve acne lesions and support clear skin surfaces.
Mechanism of action
Binds selectively to nuclear retinoic acid receptors, regulating cell differentiation to prevent microcomedone formation in pores.
Pregnancy and breastfeeding
TGA Category C: Avoid during pregnancy as safety is unconfirmed. Breastfeeding: Compatible.
What you will receive
Differin is the originator brand name, made by Galderma. We use it to identify the medicine and are not affiliated with Galderma.
- The fulfilment partner confirms whether the exact brand or an equivalent containing Adapalene is offered.
- The offered brand, manufacturer and dispatch location depend on the product, destination and partner warehouse.
- Check the final product details at checkout before confirming an order.