Dilantin
Intended to relieve neural hyperexcitability to support motor control and target seizure pathways.
Dilantin details
- Conditions
- Tonic-clonic Seizures · Complex Partial Seizures
- Alternative names
- phenytoin
- Therapeutic class
- Hydantoin Anticonvulsant
- Pharmacological class
- Antiepileptic Agent
- Known off-label uses
- trigeminal neuralgia
- Contraindications
- sinus bradycardia; severe AV block; hypersensitivity to hydantoins
- Minor side effects
- nausea; nystagmus; dizziness
- Moderate side effects
- gingival hyperplasia; ataxia; hirsutism
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Pfizer
- Onset Time
- 1–2 hours
- Duration
- 24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Aspirin; Amiodarone; Fluoxetine
- Age restrictions
- Approved for all paediatric and adult populations.
Serious side effects
Stevens-Johnson syndrome, requires immediate medical attention; severe hepatotoxicity, requires immediate medical attention
Patient summary
intended to relieve neural hyperexcitability to support motor control and target seizure pathways.
Mechanism of action
Promotes sodium efflux from motor cortex neurons by stabilising sodium channels, blocking excessive firing during seizure inception.
Pregnancy and breastfeeding
TGA Category D: Can cause fetal hydantoin syndrome. Breastfeeding: Clinically compatible.
What you will receive
Dilantin is the originator brand name, made by Pfizer. We use it to identify the medicine and are not affiliated with Pfizer.
- The fulfilment partner confirms whether the exact brand or an equivalent containing Phenytoin is offered.
- The offered brand, manufacturer and dispatch location depend on the product, destination and partner warehouse.
- Check the final product details at checkout before confirming an order.