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Efudex

Efudex

Fluorouracil

Fluorouracil cream for actinic keratosis and some skin cancers. It destroys precancerous and cancerous cells by blocking their rapid division.

Active ingredient
Fluorouracil
Route
Cutaneous use
Form
Cream
Strengths
5%

This listing uses Efudex as a reference name. A generic equivalent is supplied; its exact brand and manufacturer are confirmed before supply.

Prescription and consultation requirements for Efudex vary by destination and are determined by the fulfilment partner.

Efudex details

Alternative names
fluorouracil
Therapeutic class
Antineoplastic; Antimetabolite
Pharmacological class
Topical Fluorouracil
Minor side effects
skin erythema; burning sensation
Moderate side effects
scaling skin; swelling; hyperpigmentation
Serious side effects
severe skin ulceration, requires immediate medical attention
Dosage forms
Cream
Administration route
Cutaneous use
Supply category
Prescription-only medicine (POM)
Originator
Valeant Pharmaceuticals
Onset Time
2–4 weeks
Duration
12 hours
Storage instructions
Store below 25°C.
Age restrictions
Approved for adults.
Contraindications

pregnancy; dihydropyrimidine dehydrogenase (DPD) deficiency; hypersensitivity to fluorouracil

Patient summary

Fluorouracil cream for actinic keratosis and some skin cancers. It destroys precancerous and cancerous cells by blocking their rapid division.

Mechanism of action

Acts as a pyrimidine antagonist, selectively blocking DNA and RNA synthesis within rapidly dividing abnormal skin cells.

Pregnancy and breastfeeding

Pregnancy: Highly teratogenic. Do not use under any circumstances during pregnancy. Breastfeeding: Contraindicated.

What you will receive

Efudex is used here as a reference originator brand name to identify the medicine. We are not affiliated with the brand owner, and this listing does not offer the originator product.

  • The supplied product is a generic equivalent containing Fluorouracil, not the originator brand shown as the reference.
  • The exact generic brand, manufacturer and dispatch location are confirmed based on the product, destination and available manufacturer or partner warehouse.
  • Check the final product details at checkout before confirming an order.

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