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Neomercazole

Carbimazole

Designed to support thyroid hormone suppression to manage hyperthyroid symptoms and alleviate cardiovascular stress.

Active ingredient
Carbimazole
Route
Oral use
Form
Tablet
Strengths
5mg · 10mg

Prescription and consultation requirements for Neomercazole vary by destination and are determined by the fulfilment partner.

Neomercazole details

Alternative names
carbimazole
Therapeutic class
Antithyroid Agent
Pharmacological class
Thiourea Antithyroid
Minor side effects
nausea; headache; mild skin rash
Moderate side effects
joint pain; taste changes; mild hair loss
Dosage forms
Tablet
Administration route
Oral use
Supply category
Prescription-only medicine (POM)
Manufacturer
Abbott
Onset Time
1–2 weeks
Duration
12–24 hours
Storage instructions
Store below 25°C. Keep dry.
Drug interactions
Theophylline; Warfarin
Age restrictions
Approved for children and adults.
Contraindications

severe haematological disorders; history of pancreatitis associated with carbimazole

Serious side effects

agranulocytosis, requires immediate medical attention; acute pancreatitis, requires immediate medical attention; hepatotoxicity, requires immediate medical attention

Patient summary

designed to support thyroid hormone suppression to manage hyperthyroid symptoms and alleviate cardiovascular stress.

Mechanism of action

Rapidly metabolises into methimazole, inhibiting thyroid peroxidase to block vital iodination of tyrosine residues.

Pregnancy and breastfeeding

TGA Category D: High risk of fetal goiter and cutis aplasia. Avoid unless essential. Breastfeeding: Caution advised.