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Zytanix

Zytanix

Metolazone

Metolazone tablets for oedema and high blood pressure. It is a diuretic that works even when kidney function is poor.

Active ingredient
Metolazone
Route
Oral use
Form
Tablet
Strengths
2.5mg

Prescription and consultation requirements for Zytanix vary by destination and are determined by the fulfilment partner.

Zytanix details

Conditions
Oedema · Hypertension
Alternative names
metolazone
Therapeutic class
Thiazide-like Diuretic
Pharmacological class
Diuretic
Known off-label uses
nephrotic syndrome-associated oedema
Contraindications
anuria; severe hepatic coma; severe electrolyte depletion; sulfonamide allergy
Minor side effects
dizziness; nausea; headache
Moderate side effects
hypokalaemia; orthostatic hypotension; hyperuricaemia
Dosage forms
Tablet
Administration route
Oral use
Supply category
Prescription-only medicine (POM)
Manufacturer
Zydus Cadila
Onset Time
1–2 hours
Duration
12–24 hours
Storage instructions
Store below 25°C.
Drug interactions
Lithium; Digoxin; Furosemide
Age restrictions
Approved for adults.
Serious side effects

severe hypokalaemia, requires immediate medical attention; acute pancreatitis, requires immediate medical attention

Patient summary

Metolazone tablets for oedema and high blood pressure. It is a diuretic that works even when kidney function is poor.

Mechanism of action

Blocks active sodium reabsorption in the distal tubules, inducing renal clearance of water and salt.

Pregnancy and breastfeeding

Pregnancy: May contract maternal fluid volume. Breastfeeding: Expelled in low amounts.