Entresto

Formulated to alleviate cardiac workload to support ventricular recovery and target neurohormonal pathways.

Dosage

Pack size

You will receive a quality generic equivalent of Entresto, depending on stock.

Prescription and consultation requirements for Entresto vary by destination and are determined by the fulfilment partner.

Entresto details

Condition: Heart Failure
Alternative names: sacubitril, valsartan
Therapeutic class: Neprilysin Inhibitor, Angiotensin II Receptor Antagonist Combination
Pharmacological class: Angiotensin Receptor-Neprilysin Inhibitor (ARNI)
Contraindications: history of angioedema; concurrent use of ACE inhibitors; pregnancy
Minor side effects: dizziness; cough; headache
Moderate side effects: hyperkalaemia; hypotension; renal impairment
Serious side effects: angioedema, requires immediate medical attention
Dosage forms: Tablet
Administration route: Oral use
Supply category: Prescription-only medicine (POM)
Originator: Novartis
Onset Time: 1–2 hours
Duration: 12 hours
Storage instructions: Store below 25°C.
Drug interactions: ACE Inhibitors; Lithium; Potassium Supplements
Age restrictions: Approved for paediatric and adult patients.

Patient summary

formulated to alleviate cardiac workload to support ventricular recovery and target neurohormonal pathways.

Mechanism of action

Sacubitril blocks neprilysin to raise vasoprotective peptides while valsartan blocks vasoconstricting AT1 receptors.

Pregnancy and breastfeeding

TGA Category D: High risk of fetal toxicity and death. Contraindicated in pregnancy. Breastfeeding: Not recommended.

Entresto is the originator brand name, made by Novartis. We use it to identify the medicine and are not affiliated with Novartis.

The fulfilment partner confirms whether the exact brand or an equivalent containing Sacubitril / Valsartan is offered.
The offered brand, manufacturer and dispatch location depend on the product, destination and partner warehouse.
Check the final product details at checkout before confirming an order.