Entresto
Sacubitril and valsartan tablets for heart failure. They combine two actions to reduce strain on a failing heart.
- Category
- Heart & Blood Pressure
- Active ingredients
- Sacubitril · Valsartan
- Route
- Oral use
- Form
- Tablet
- Strengths
- 24mg + 26mg
This listing uses Entresto as a reference name. A generic equivalent is supplied; its exact brand and manufacturer are confirmed before supply.
Prescription and consultation requirements for Entresto vary by destination and are determined by the fulfilment partner.
Entresto details
- Condition
- Heart Failure
- Alternative names
- sacubitril, valsartan
- Therapeutic class
- Neprilysin Inhibitor, Angiotensin II Receptor Antagonist Combination
- Pharmacological class
- Angiotensin Receptor-Neprilysin Inhibitor (ARNI)
- Contraindications
- history of angioedema; concurrent use of ACE inhibitors; pregnancy
- Minor side effects
- dizziness; cough; headache
- Moderate side effects
- hyperkalaemia; hypotension; renal impairment
- Serious side effects
- angioedema, requires immediate medical attention
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Novartis
- Onset Time
- 1–2 hours
- Duration
- 12 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- ACE Inhibitors; Lithium; Potassium Supplements
- Age restrictions
- Approved for paediatric and adult patients.
Patient summary
Sacubitril and valsartan tablets for heart failure. They combine two actions to reduce strain on a failing heart.
Mechanism of action
Sacubitril blocks neprilysin to raise vasoprotective peptides while valsartan blocks vasoconstricting AT1 receptors.
Pregnancy and breastfeeding
Pregnancy: High risk of fetal toxicity and death. Contraindicated in pregnancy. Breastfeeding: Not recommended.
What you will receive
Entresto is used here as a reference originator brand name to identify the medicine. We are not affiliated with the brand owner, and this listing does not offer the originator product.
- The supplied product is a generic equivalent containing Sacubitril / Valsartan, not the originator brand shown as the reference.
- The exact generic brand, manufacturer and dispatch location are confirmed based on the product, destination and available manufacturer or partner warehouse.
- Check the final product details at checkout before confirming an order.