Letairis
Developed to target pulmonary hypertension to alleviate respiratory stress.
- Category
- Heart & Blood Pressure
- Active ingredient
- Ambrisentan
- Route
- Oral use
- Form
- Tablet
- Strengths
- 5mg
You will receive a quality generic equivalent of Letairis, depending on stock.
Prescription and consultation requirements for Letairis vary by destination and are determined by the fulfilment partner.
Letairis details
- Condition
- Pulmonary Arterial Hypertension
- Alternative names
- Volibris
- Therapeutic class
- Endothelin Receptor Antagonist
- Pharmacological class
- Endothelin Receptor Antagonist
- Contraindications
- pregnancy; severe hepatic impairment; hypersensitivity to components
- Minor side effects
- headache; nasal congestion; flushing
- Moderate side effects
- peripheral oedema; palpitations; constipation
- Dosage forms
- Tablet
- Administration route
- Oral use
- Patient summary
- developed to target pulmonary hypertension to alleviate respiratory stress.
- Supply category
- Prescription-only medicine (POM)
- Originator
- Gilead Sciences
- Onset Time
- 2–4 weeks
- Duration
- Long-term usage
- Storage instructions
- Store at room temperature.
- Drug interactions
- cyclosporine
- Age restrictions
- Adults.
- Pregnancy and breastfeeding
- Pregnancy: Contraindicated (teratogenic). Breastfeeding: Not recommended.
Precautions and warnings
requires liver function monitoring; risk of birth defects; requires consistent contraceptive use in females
Serious side effects
liver failure, requires immediate medical attention; pulmonary oedema, requires immediate medical attention
Mechanism of action
Ambrisentan acts as a selective endothelin receptor antagonist. By blocking the binding of endothelin-1 to receptors in the pulmonary artery walls, it promotes vasodilation and helps manage elevated pressure levels.
What you will receive
Letairis is the originator brand name, made by Gilead Sciences. We use it to identify the medicine and are not affiliated with Gilead Sciences.
- The fulfilment partner confirms whether the exact brand or an equivalent containing Ambrisentan is offered.
- The offered brand, manufacturer and dispatch location depend on the product, destination and partner warehouse.
- Check the final product details at checkout before confirming an order.