Letairis
Ambrisentan tablets for pulmonary arterial hypertension. It blocks a chemical that constricts lung arteries, easing strain on the heart.
- Category
- Heart & Blood Pressure
- Active ingredient
- Ambrisentan
- Route
- Oral use
- Form
- Tablet
- Strengths
- 5mg
This listing uses Letairis as a reference name. A generic equivalent is supplied; its exact brand and manufacturer are confirmed before supply.
Prescription and consultation requirements for Letairis vary by destination and are determined by the fulfilment partner.
Letairis details
- Condition
- Pulmonary Arterial Hypertension
- Alternative names
- Volibris
- Therapeutic class
- Endothelin Receptor Antagonist
- Pharmacological class
- Endothelin Receptor Antagonist
- Contraindications
- pregnancy; severe hepatic impairment; hypersensitivity to components
- Minor side effects
- headache; nasal congestion; flushing
- Moderate side effects
- peripheral oedema; palpitations; constipation
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Gilead Sciences
- Onset Time
- 2–4 weeks
- Duration
- Long-term usage
- Storage instructions
- Store at room temperature.
- Drug interactions
- cyclosporine
- Age restrictions
- Adults.
- Pregnancy and breastfeeding
- Pregnancy: Contraindicated (teratogenic). Breastfeeding: Not recommended.
Precautions and warnings
requires liver function monitoring; risk of birth defects; requires consistent contraceptive use in females
Serious side effects
liver failure, requires immediate medical attention; pulmonary oedema, requires immediate medical attention
Patient summary
Ambrisentan tablets for pulmonary arterial hypertension. It blocks a chemical that constricts lung arteries, easing strain on the heart.
Mechanism of action
Ambrisentan acts as a selective endothelin receptor antagonist. By blocking the binding of endothelin-1 to receptors in the pulmonary artery walls, it promotes vasodilation and helps manage elevated pressure levels.
What you will receive
Letairis is used here as a reference originator brand name to identify the medicine. We are not affiliated with the brand owner, and this listing does not offer the originator product.
- The supplied product is a generic equivalent containing Ambrisentan, not the originator brand shown as the reference.
- The exact generic brand, manufacturer and dispatch location are confirmed based on the product, destination and available manufacturer or partner warehouse.
- Check the final product details at checkout before confirming an order.