Leukeran
Chlorambucil tablets for chronic lymphocytic leukaemia and Hodgkin lymphoma. It damages the DNA inside cancer cells so they die off.
- Category
- Oncology Support
- Active ingredient
- Chlorambucil
- Route
- Oral use
- Form
- Tablet
- Strengths
- 2mg
You will receive a quality generic equivalent of Leukeran, depending on stock.
Prescription and consultation requirements for Leukeran vary by destination and are determined by the fulfilment partner.
Leukeran details
- Conditions
- Chronic Lymphocytic Leukaemia · Hodgkin's Lymphoma
- Alternative names
- chlorambucil
- Therapeutic class
- Alkylating Agent
- Pharmacological class
- Nitrogen Mustard
- Known off-label uses
- nephrotic syndrome
- Contraindications
- severe bone marrow suppression; previous resistance to chlorambucil
- Minor side effects
- nausea; vomiting; alopecia
- Moderate side effects
- myelosuppression; skin rash; fever
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- GlaxoSmithKline
- Onset Time
- 2–3 weeks
- Duration
- 24 hours
- Storage instructions
- Store between 2°C and 8°C.
- Drug interactions
- Live Vaccines
- Age restrictions
- Approved for adults. Used in paediatric populations under strict protocols.
Serious side effects
severe myelosuppression, requires immediate medical attention; acute leukaemia development, requires immediate medical attention; pulmonary fibrosis, requires immediate medical attention
Patient summary
Chlorambucil tablets for chronic lymphocytic leukaemia and Hodgkin lymphoma. It damages the DNA inside cancer cells so they die off.
Mechanism of action
Forms covalent cross-links with cellular DNA, disrupting replication and transcription to trigger programmed death in neoplastic cells.
Pregnancy and breastfeeding
TGA Category D: High risk of fetal toxicity. Do not use in pregnancy. Breastfeeding: Contraindicated.
What you will receive
Leukeran is the originator brand name, made by GlaxoSmithKline. We use it to identify the medicine and are not affiliated with GlaxoSmithKline.
- The fulfilment partner confirms whether the exact brand or an equivalent containing Chlorambucil is offered.
- The offered brand, manufacturer and dispatch location depend on the product, destination and partner warehouse.
- Check the final product details at checkout before confirming an order.