Leukeran
Chlorambucil tablets for chronic lymphocytic leukaemia and Hodgkin lymphoma. It damages the DNA inside cancer cells so they die off.
- Category
- Oncology Support
- Active ingredient
- Chlorambucil
- Route
- Oral use
- Form
- Tablet
- Strengths
- 2mg
This listing uses Leukeran as a reference name. A generic equivalent is supplied; its exact brand and manufacturer are confirmed before supply.
Prescription and consultation requirements for Leukeran vary by destination and are determined by the fulfilment partner.
Leukeran details
- Conditions
- Chronic Lymphocytic Leukaemia · Hodgkin's Lymphoma
- Alternative names
- chlorambucil
- Therapeutic class
- Alkylating Agent
- Pharmacological class
- Nitrogen Mustard
- Known off-label uses
- nephrotic syndrome
- Contraindications
- severe bone marrow suppression; previous resistance to chlorambucil
- Minor side effects
- nausea; vomiting; alopecia
- Moderate side effects
- myelosuppression; skin rash; fever
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- GlaxoSmithKline
- Onset Time
- 2–3 weeks
- Duration
- 24 hours
- Storage instructions
- Store between 2°C and 8°C.
- Drug interactions
- Live Vaccines
- Age restrictions
- Approved for adults. Used in paediatric populations under strict protocols.
Serious side effects
severe myelosuppression, requires immediate medical attention; acute leukaemia development, requires immediate medical attention; pulmonary fibrosis, requires immediate medical attention
Patient summary
Chlorambucil tablets for chronic lymphocytic leukaemia and Hodgkin lymphoma. It damages the DNA inside cancer cells so they die off.
Mechanism of action
Forms covalent cross-links with cellular DNA, disrupting replication and transcription to trigger programmed death in neoplastic cells.
Pregnancy and breastfeeding
Pregnancy: High risk of fetal toxicity. Do not use in pregnancy. Breastfeeding: Contraindicated.
What you will receive
Leukeran is used here as a reference originator brand name to identify the medicine. We are not affiliated with the brand owner, and this listing does not offer the originator product.
- The supplied product is a generic equivalent containing Chlorambucil, not the originator brand shown as the reference.
- The exact generic brand, manufacturer and dispatch location are confirmed based on the product, destination and available manufacturer or partner warehouse.
- Check the final product details at checkout before confirming an order.