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Leukeran

Chlorambucil

Designed to support neoplastic disease management to manage lymphocytic levels and alleviate tumour replication.

Active ingredient
Chlorambucil
Route
Oral use
Form
Tablet
Strengths
2mg

You will receive a quality generic equivalent of Leukeran, depending on stock.

Prescription and consultation requirements for Leukeran vary by destination and are determined by the fulfilment partner.

Leukeran details

Alternative names
chlorambucil
Therapeutic class
Alkylating Agent
Pharmacological class
Nitrogen Mustard
Known off-label uses
nephrotic syndrome
Contraindications
severe bone marrow suppression; previous resistance to chlorambucil
Minor side effects
nausea; vomiting; alopecia
Moderate side effects
myelosuppression; skin rash; fever
Dosage forms
Tablet
Administration route
Oral use
Supply category
Prescription-only medicine (POM)
Originator
GlaxoSmithKline
Onset Time
2–3 weeks
Duration
24 hours
Storage instructions
Store between 2°C and 8°C.
Drug interactions
Live Vaccines
Age restrictions
Approved for adults. Used in paediatric populations under strict protocols.
Serious side effects

severe myelosuppression, requires immediate medical attention; acute leukaemia development, requires immediate medical attention; pulmonary fibrosis, requires immediate medical attention

Patient summary

designed to support neoplastic disease management to manage lymphocytic levels and alleviate tumour replication.

Mechanism of action

Forms covalent cross-links with cellular DNA, disrupting replication and transcription to trigger programmed death in neoplastic cells.

Pregnancy and breastfeeding

TGA Category D: High risk of fetal toxicity. Do not use in pregnancy. Breastfeeding: Contraindicated.

What you will receive

Leukeran is the originator brand name, made by GlaxoSmithKline. We use it to identify the medicine and are not affiliated with GlaxoSmithKline.

  • The fulfilment partner confirms whether the exact brand or an equivalent containing Chlorambucil is offered.
  • The offered brand, manufacturer and dispatch location depend on the product, destination and partner warehouse.
  • Check the final product details at checkout before confirming an order.

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