Methotrexate Tablets
Methotrexate tablets for rheumatoid arthritis and psoriasis. It calms the immune system's attack on joints and skin.
- Category
- Oncology Support
- Active ingredient
- Methotrexate
- Route
- Oral use
- Form
- Tablet
- Strengths
- 2.5mg · 5mg · 7.5mg · 10mg
The exact manufacturer offered is confirmed by the fulfilment partner before supply.
Prescription and consultation requirements for Methotrexate Tablets vary by destination and are determined by the fulfilment partner.
Methotrexate Tablets details
- Conditions
- Rheumatoid Arthritis · Psoriasis · Acute Lymphocytic Leukaemia
- Alternative names
- rheumatrex
- Therapeutic class
- Folate Analog Antimetabolite
- Pharmacological class
- Antineoplastic and Antirheumatic
- Known off-label uses
- ectopic pregnancy; crohn's disease
- Minor side effects
- nausea; mouth sores; fatigue
- Moderate side effects
- myelosuppression; elevated liver enzymes; alopecia
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Onset Time
- 3–6 weeks
- Duration
- 12–24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- NSAIDs; Penicillin; Trimethoprim
- Age restrictions
- Approved for paediatric and adult populations.
Contraindications
pregnancy; severe renal impairment; severe bone marrow suppression; chronic liver disease
Serious side effects
severe hepatotoxicity, requires immediate medical attention; pulmonary fibrosis, requires immediate medical attention; severe pancytopenia, requires immediate medical attention
Patient summary
Methotrexate tablets for rheumatoid arthritis and psoriasis. It calms the immune system's attack on joints and skin.
Mechanism of action
Inhibits dihydrofolate reductase, preventing synthesis of tetrahydrofolate required for DNA synthesis inside cellular structures.
Pregnancy and breastfeeding
Pregnancy: Highly teratogenic and abortifacient. Highly contraindicated. Breastfeeding: Contraindicated.
What you will receive
Methotrexate Tablets is a generic medicine sold under the name of its active ingredient, Methotrexate, rather than under a brand.
- The fulfilment partner confirms the offered manufacturer and product before supply.
- Check the active ingredient, strength, form and pack shown at checkout before confirming an order.