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Arava

Leflunomide

Formulated to alleviate joint inflammation to support physical mobility and target progressive skeletal damage.

Active ingredient
Leflunomide
Route
Oral use
Form
Tablet
Strengths
10mg · 20mg

You will receive a quality generic equivalent of Arava, depending on stock.

Prescription and consultation requirements for Arava vary by destination and are determined by the fulfilment partner.

Arava details

Alternative names
leflunomide
Therapeutic class
Disease-Modifying Antirheumatic Drug (DMARD)
Pharmacological class
Pyrimidine Synthesis Inhibitor
Known off-label uses
psoriatic arthritis
Contraindications
pregnancy; severe hepatic impairment; severe immunodeficiency
Minor side effects
diarrhoea; nausea; headache
Moderate side effects
hair thinning; elevated liver enzymes; elevated blood pressure
Dosage forms
Tablet
Administration route
Oral use
Supply category
Prescription-only medicine (POM)
Originator
Sanofi-Aventis
Onset Time
4–8 weeks
Duration
1–2 weeks
Storage instructions
Store below 25°C.
Drug interactions
Cholestyramine; Warfarin; Methotrexate
Age restrictions
Approved for adults.
Serious side effects

severe hepatotoxicity, requires immediate medical attention; pancytopenia, requires immediate medical attention

Patient summary

formulated to alleviate joint inflammation to support physical mobility and target progressive skeletal damage.

Mechanism of action

Inhibits the mitochondrial enzyme dihydroorotate dehydrogenase, blocking pyrimidine synthesis and suppressing autoimmune T-cell proliferation.

Pregnancy and breastfeeding

TGA Category X: Highly teratogenic. Do not use under any circumstances during pregnancy. Breastfeeding: Contraindicated.

What you will receive

Arava is the originator brand name, made by Sanofi-Aventis. We use it to identify the medicine and are not affiliated with Sanofi-Aventis.

  • The fulfilment partner confirms whether the exact brand or an equivalent containing Leflunomide is offered.
  • The offered brand, manufacturer and dispatch location depend on the product, destination and partner warehouse.
  • Check the final product details at checkout before confirming an order.

How we compare medicine brands and generics