Arava
Leflunomide tablets for rheumatoid arthritis. It stays in the body for weeks after stopping, so side effects may persist long after the last dose.
- Categories
- Pain & Anti-inflammatories · Autoimmune Support
- Active ingredient
- Leflunomide
- Route
- Oral use
- Form
- Tablet
- Strengths
- 10mg · 20mg
This listing uses Arava as a reference name. A generic equivalent is supplied; its exact brand and manufacturer are confirmed before supply.
Prescription and consultation requirements for Arava vary by destination and are determined by the fulfilment partner.
Arava details
- Condition
- Rheumatoid Arthritis
- Alternative names
- leflunomide
- Therapeutic class
- Disease-Modifying Antirheumatic Drug (DMARD)
- Pharmacological class
- Pyrimidine Synthesis Inhibitor
- Known off-label uses
- psoriatic arthritis
- Contraindications
- pregnancy; severe hepatic impairment; severe immunodeficiency
- Minor side effects
- diarrhoea; nausea; headache
- Moderate side effects
- hair thinning; elevated liver enzymes; elevated blood pressure
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Sanofi-Aventis
- Onset Time
- 4–8 weeks
- Duration
- 1–2 weeks
- Storage instructions
- Store below 25°C.
- Drug interactions
- Cholestyramine; Warfarin; Methotrexate
- Age restrictions
- Approved for adults.
Serious side effects
severe hepatotoxicity, requires immediate medical attention; pancytopenia, requires immediate medical attention
Patient summary
Leflunomide tablets for rheumatoid arthritis. It stays in the body for weeks after stopping, so side effects may persist long after the last dose.
Mechanism of action
Inhibits the mitochondrial enzyme dihydroorotate dehydrogenase, blocking pyrimidine synthesis and suppressing autoimmune T-cell proliferation.
Pregnancy and breastfeeding
Pregnancy: Highly teratogenic. Do not use under any circumstances during pregnancy. Breastfeeding: Contraindicated.
What you will receive
Arava is used here as a reference originator brand name to identify the medicine. We are not affiliated with the brand owner, and this listing does not offer the originator product.
- The supplied product is a generic equivalent containing Leflunomide, not the originator brand shown as the reference.
- The exact generic brand, manufacturer and dispatch location are confirmed based on the product, destination and available manufacturer or partner warehouse.
- Check the final product details at checkout before confirming an order.