Vastarel
Formulated to alleviate coronary myocardial ischaemia to support cardiac oxygen efficiency and target stable angina.
- Category
- Heart & Blood Pressure
- Active ingredient
- Trimetazidine
- Route
- Oral use
- Form
- Tablet
- Strengths
- 20mg
Prescription and consultation requirements for Vastarel vary by destination and are determined by the fulfilment partner.
Vastarel details
- Condition
- Angina Pectoris Stable
- Alternative names
- trimetazidine
- Therapeutic class
- Anti-ischaemic Agent
- Pharmacological class
- Fatty Acid Oxidation Inhibitor
- Known off-label uses
- vertigo; tinnitus
- Contraindications
- parkinson's disease; uncontrolled extrapyramidal symptoms; severe renal failure
- Minor side effects
- nausea; headache; dizziness
- Moderate side effects
- indigestion; mild rash; diarrhoea
- Serious side effects
- drug-induced parkinsonism, requires immediate medical attention
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Manufacturer
- Servier
- Onset Time
- 1–2 weeks
- Duration
- 12–24 hours
- Storage instructions
- Store below 25°C.
- Age restrictions
- Approved for adults.
Patient summary
formulated to alleviate coronary myocardial ischaemia to support cardiac oxygen efficiency and target stable angina.
Mechanism of action
Blocks long-chain 3-ketoacyl-CoA thiolase, shifting myocardial metabolism from fatty acid to glucose oxidation to preserve energy.
Pregnancy and breastfeeding
TGA Category C: Use if potential benefits outweigh risks. Breastfeeding: Consult a doctor.