Diane 35

Buy Diane 35
diane 35

$62.65

  • Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
  • Prescription: Included
  • Availability: In Stock

Diane-35 is a combination hormonal medication used to treat acne, hirsutism, and other androgen-related conditions in women, while also functioning as a contraceptive. It contains cyproterone acetate and ethinyl estradiol, which regulate hormones and suppress ovulation

Table of contents

Diane 35 is a prescription medication primarily used to treat moderate to severe Acne in women, particularly when the acne is related to hormonal factors and other treatments have proven ineffective. Its therapeutic action stems from its dual-hormone composition, which includes cyproterone acetate, an anti-androgen, and ethinylestradiol, an estrogen. This combination works by regulating hormone levels that can contribute to acne and excessive hair growth. While its primary approved use is for these dermatological conditions, it is also a well-established oral contraceptive. It is specifically indicated for women of reproductive age who also require reliable contraception, offering a two-fold benefit for those managing both skin concerns and family planning.

Diane 35 Overview
Active Ingredients Cyproterone Acetate 2 mg / Ethinylestradiol 0.035 mg
Drug Class Hormonal Contraceptive & Anti-androgen
Primary Uses Moderate to severe acne in women; androgen-related symptoms; contraception
Available Forms Film-coated tablet
Typical Strength 2 mg/0.035 mg
Regulatory Status Prescription (Rx)
Administration Oral, once daily
Common Side Effects Headache, nausea, breast tenderness, mood changes
Serious Side Effects Blood clots, stroke, heart attack, liver problems

Understanding Diane 35

Diane 35 is a branded pharmaceutical product that combines two active hormones: cyproterone acetate and ethinylestradiol. It is classified as a hormonal anti-androgen and contraceptive. In many regions, including the UAE, Diane 35 is strictly a prescription medication due to its potent hormonal effects and associated risks, such as an increased potential for venous thromboembolism. It was developed by the pharmaceutical company Bayer and is specifically designed for women whose acne is caused or worsened by androgens (male hormones present in both sexes). Its use is generally reserved for cases where topical treatments or Antibiotics have not been successful, positioning it as a second-line option with the added benefit of reliable contraception.

How Diane 35 Works to Manage Hormonal Acne

The effectiveness of Diane 35 lies in the complementary actions of its two ingredients. Cyproterone acetate acts as an anti-androgen, meaning it blocks the effects of androgens like testosterone in the body. Androgens can stimulate the sebaceous glands in the skin to produce excess oil (sebum), which is a primary factor in the development of acne. By binding to androgen receptors, cyproterone acetate reduces this sebum production. Ethinylestradiol, a synthetic estrogen, works by suppressing the body's own production of androgens from the ovaries. It also helps regulate the menstrual cycle, making the contraceptive effect predictable.

From a pharmacokinetic perspective, the medication is taken orally and absorbed through the gastrointestinal tract. The onset of action for acne treatment is not immediate; it typically takes several cycles (2-3 months) to see significant skin improvement as the hormonal balance shifts and skin cell turnover occurs. The duration of action is about 24 hours, which is why a daily dose is required. The body metabolizes the hormones primarily in the liver, which is why liver health is an important consideration before prescription.

Clinical Applications and Treatment Positioning

Diane 35 is specifically indicated for women with moderate to severe acne that is known or suspected to be hormonal in origin. This often includes acne that flares up around the menstrual cycle or appears predominantly on the lower face, jawline, and neck. It is an effective choice because it directly targets the hormonal driver of the condition, unlike topical treatments that address surface bacteria and inflammation. For this specific patient group, it can be a first-line systemic therapy when other options have failed.

Its role extends to managing other androgen-related conditions, such as Hirsutism (excessive hair growth in a male-like pattern). In clinical practice, it is often prescribed when a woman has both a need for acne treatment and a desire for hormonal contraception. However, due to the increased risk of blood clots compared to some other contraceptives, it is not typically recommended as a first-choice contraceptive for women without these specific androgen-related concerns. Its use is a considered decision made by a doctor after evaluating individual risk factors.

Determining Patient Suitability

Diane 35 is suitable for women of reproductive age who are experiencing hormonally influenced acne and who also need contraception. A doctor will assess suitability based on medical history, with particular attention to contraindications. Key factors that would make Diane 35 unsuitable include a personal history of blood clots, certain types of migraines (especially with aura), severe hypertension, liver disease, or a history of certain cancers like Breast Cancer. Smoking, especially in women over 35, significantly increases the risks associated with this medication.

For special populations, Diane 35 is not used during pregnancy or breastfeeding. It is generally not prescribed for adolescents until after their menstrual cycles have become well-established. Women with conditions like diabetes or elevated cholesterol levels require careful monitoring, as the medication can influence these parameters. The decision to use Diane 35 is a balance between the therapeutic benefits for skin conditions and the individual's overall health profile.

Taking Diane 35 Effectively

The standard regimen for Diane 35 involves taking one tablet daily at approximately the same time each day for 21 consecutive days, followed by a 7-day break during which a withdrawal bleed (like a period) occurs. Adherence to this schedule is crucial for both contraceptive reliability and consistent hormonal suppression for acne management. The why behind taking it at the same time is less about contraceptive failure-which is unlikely with a combined pill if you're only a few hours late-and more about building a strong habit to prevent missed doses altogether.

If a dose is missed, the principles of management depend on how much time has passed. Generally, taking the missed pill as soon as you remember and the next one at the usual time is sufficient if it's within 12-24 hours. Beyond 24 hours, additional contraceptive precautions may be needed. These specifics should be clearly outlined in the medication's package leaflet and discussed with a pharmacist or doctor. For storage, keep the blister pack at room temperature, protected from moisture and light, and always keep it in its original packaging to avoid confusion with other medications. When traveling, carry it in your hand luggage to ensure it's not lost.

Understanding Potential Side Effects

Many side effects of Diane 35 are directly linked to its hormonal mechanism. Common but usually temporary effects include nausea, breast tenderness, headaches, and mood changes. These often occur as the body adjusts to the new hormone levels during the first few months of treatment. They are typically manageable and may subside. For example, taking the pill with food can help reduce nausea, and wearing a supportive bra may ease breast tenderness.

Some side effects are more serious and require immediate medical attention. The most significant risk is the formation of blood clots (venous thromboembolism), which, while rare, is higher with Diane 35 than with some other contraceptives. Symptoms of a clot include sudden leg Pain or swelling, sharp chest pain, coughing up blood, or sudden shortness of breath. Other serious effects can include signs of a stroke (sudden weakness, vision changes, slurred speech), severe abdominal pain (indicating possible liver problems), or significant changes in mood, including Depression. Understanding these distinctions helps users respond appropriately to their body's signals.

Frequently Asked Questions

How long does it take for Diane 35 to clear acne?

Most women begin to see an improvement in their acne after 2 to 3 months of consistent use. It can take up to 6 months to see the full therapeutic benefit, as this timeline allows for hormonal balance to be achieved and existing acne lesions to heal.

Can I use Diane 35 solely for acne if I don't need contraception?

While Diane 35 is highly effective for hormonal acne, it is almost always prescribed with the understanding that it also provides contraception. Due to its associated risks, doctors typically reserve it for women who also need a contraceptive method. Other anti-androgen medications might be considered for acne treatment without the contraceptive component.

What is the difference between Diane 35 and a regular birth control pill?

The key difference is the active ingredient cyproterone acetate, which has a specific anti-androgen effect. Many regular combined contraceptive pills use other progestins that do not have this strong anti-testosterone activity. This makes Diane 35 particularly suited for treating androgen-related conditions.

Will I gain weight on Diane 35?

Clinical studies have not consistently shown that Diane 35 causes significant weight gain. Some women may experience fluid retention initially, which can lead to a small amount of weight gain, but this often stabilizes. Major weight changes are uncommon and should be discussed with a doctor.

What should I do if I miss my period while taking Diane 35?

If you have taken all your pills correctly and miss a withdrawal bleed, it is not usually a cause for concern, especially during the first few cycles. However, if you miss two consecutive periods, or if you suspect you may have missed pills earlier in the cycle, you should take a pregnancy test to be safe and consult your doctor.

Can I drink alcohol while taking Diane 35?

Moderate alcohol consumption is generally considered acceptable. However, since both the medication and alcohol are processed by the liver, heavy drinking is not advised as it can place additional strain on the liver and potentially increase the risk of side effects.

How does Diane 35 affect my fertility after I stop taking it?

Diane 35 does not have a long-term impact on fertility. After discontinuation, your natural menstrual cycle should return, usually within one to three months. You can ovulate very soon after stopping, so alternative contraception should be used immediately if pregnancy is not desired.

Is it normal to experience spotting between periods?

Breakthrough bleeding or spotting is relatively common, especially during the first few packs as your body adjusts to the hormones. If it persists beyond the first three months, or if the bleeding becomes heavy, it is advisable to consult your healthcare provider to ensure there are no other underlying issues.

Glossary

Anti-androgen
A substance that blocks the effects of androgens (male hormones) in the body. In Diane 35, cyproterone acetate acts as an anti-androgen to reduce sebum production and improve acne.
Venous Thromboembolism (VTE)
A condition involving the formation of a blood clot in a vein, which can be serious if the clot travels to the lungs. This is a known, albeit rare, risk associated with combined hormonal contraceptives like Diane 35.
Hirsutism
The growth of excessive, dark, or coarse hair in women in a male-like pattern (e.g., on the face, chest, or back). It is an androgen-related condition that Diane 35 can help manage.
Withdrawal Bleed
The monthly bleeding that occurs during the 7-day break from active pills. It is not a true menstrual period but a response to the sudden drop in hormone levels.

Important Safety Information

The content provided about Diane 35 is for educational purposes and should not be interpreted as personal medical advice. This information is not a substitute for a consultation with a qualified healthcare professional. Any decisions regarding treatment, including the management of conditions beyond its approved indications, must be made under the guidance of a doctor. We operate on the assumption that our readers are responsible individuals capable of making informed health choices. Our online pharmacy service facilitates access to Diane 35 for those who may face barriers with local prescription schemes or are seeking specific treatment options. It is essential to consult your physician before initiating, altering, or discontinuing any course of medication.


Can You Buy Diane 35 in UAE Without a Prescription?

Diane 35 is available in UAE with a valid prescription from a licensed healthcare professional. Alternatively, you can order Diane 35 from our overseas online pharmacy. We work with trusted international suppliers and ensure full compliance with UAE import regulations — no local prescription required for personal use.

Why You Can Import Diane 35 into UAE

UAE regulations allow importing Diane 35 for personal use, provided quantities stay within approved limits and are supported by a valid prescription, which our service helps arrange. This offers safe, legal access to reliable generic and branded Diane 35 options at competitive prices.

How to Get Beneficial Diane 35 Refills

Managing your Diane 35 refills is simple and hassle-free. Reorder through your account to enjoy a 10% discount on every refill and reliable delivery.

Exclusive Benefits for UAE Customers

Customers in UAE enjoy personalised support and fast, discreet delivery fully compliant with UAE import laws. Take advantage of special shipping discounts and reliable Diane 35 delivery across Emirates, including Dubai, Abu Dhabi, Sharjah, Al Ain, Ajman, Ras Al Khaimah.


How to Buy Diane 35 | Cyproterone Acetate And Ethinylestradiol from our Online Pharmacy

Buying Diane 35 | Cyproterone Acetate And Ethinylestradiol on our site is simple. Just choose your dose and tablet quantity — the total price updates instantly. Click Add to Cart to add your order, then continue shopping or go to checkout. On the Payment Page, complete your purchase using our secure, encrypted system to keep your details private.

Diane 35 / Cyproterone-acetate-and-ethinylestradiol pills are made from high-quality ingredients and tested to meet WHO and The UAE Ministry of Health (MOH) standards. Orders ship from outside UAE under international prescription rules, allowing us to provide top quality and affordable prices safely.

Reviews

4.74/195
Diane 35

My doctor put me on this for my hormonal acne. The first month was not good, my skin got even worse. But I pushed through, and by the fourth month, my face was clearer than it has been in years. I did gain a couple of kilos though, which is the main drawback.

Hanan A. (Hanan_KSA) Dammam, Saudi Arabia

I was prescribed Diane-35 for my PCOS symptoms. It definitely helped with the acne aspect. However, after about a year, I felt my moods were all over the place. It worked for my skin, but I'm talking to my doctor about alternatives because of the emotional side effects.

Alya A. (Alya_DXB) Dubai, UAE

I've been taking this for about six weeks. I can see the breakouts are becoming smaller and drying up faster, which is a good sign. But I've noticed I feel more bloated than usual since I started. Hoping that settles down over time.

Lina H. (Lina_Jo) Amman, Jordan

This was really effective for my severe acne. I was on it for about two years and my skin was great. I decided to take a break to see how my body would react, and my skin is still mostly clear six months later. I didn't experience any weight gain, luckily.

Fatima A. (Fatima_KW) Salwa, Kuwait

A word of warning: the initial breakout is real. My dermatologist warned me and it still made me want to quit. Around week 6 or 7, things finally started to improve. It's a slow process, not an overnight fix.

Sara A. (Sara_QA) Doha, Qatar

Used it for 5 years. It kept my skin under control but I recently stopped. I was concerned about being on a hormone pill for that long after reading some articles. It served its purpose but I'm looking for non-hormonal solutions now.

Noor A. (Noor_Oman) Muscat, Oman

Write your review

We accept reviews only from exisiting customers


We appreciate your insights and personal encounters with the Diane 35 medication that has been part of your health journey. Recognizing that insights from individuals with similar experiences can play a pivotal role in making informed health choices, we highly value your perspective. That's why we invite you to impart your genuine reflections about the Diane 35 that has been instrumental in managing your health.

Your perceptions of Diane 35 | Cyproterone Acetate And Ethinylestradiol can guide others in discerning the best options for their well-being, enhancing their therapeutic journey. We staunchly reckon that collective patient experiences can drive meaningful change in healthcare and the realm of online drugstores. Consequently, we are dedicated to giving your opinions the stage they deserve. Spare a moment to pen down your thoughts, assisting us in fortifying a community where members empower and uplift each other.


Information provided by Dr. Nithya Priya Raju. Reviewed by Dr. Mohamed El Khouly