Baclosign
Baclofen tablets for spasticity and muscle spasms. It works at the spinal cord to reduce the signals that cause muscles to tighten.
- Category
- Pain & Anti-inflammatories
- Active ingredient
- Baclofen
- Route
- Oral use
- Form
- Tablet
- Strengths
- 10mg · 25mg
Prescription and consultation requirements for Baclosign vary by destination and are determined by the fulfilment partner.
Baclosign details
- Conditions
- Spasticity · Muscle Spasms
- Alternative names
- baclofen
- Therapeutic class
- Skeletal Muscle Relaxant
- Pharmacological class
- GABA-B Receptor Agonist
- Known off-label uses
- hiccups
- Contraindications
- hypersensitivity to baclofen
- Minor side effects
- somnolence; dizziness; nausea
- Moderate side effects
- muscle weakness; fatigue; confusion
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Manufacturer
- Signature Pharma
- Onset Time
- 1–2 hours
- Duration
- 4–8 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Alcohol; Antihistamines; CNS Depressants
- Age restrictions
- Approved for paediatric and adult populations.
Serious side effects
seizure, requires immediate medical attention; severe respiratory depression, requires immediate medical attention
Patient summary
Baclofen tablets for spasticity and muscle spasms. It works at the spinal cord to reduce the signals that cause muscles to tighten.
Mechanism of action
Inhibits synaptic transmission at spinal cord level by binding to GABA-B receptors, reducing excitatory neurotransmitter release.
Pregnancy and breastfeeding
Pregnancy: Use if potential benefits justify risks. Breastfeeding: Confirm breastfeeding suitability with a qualified clinician or pharmacist before use.