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Glucovance

Metformin · Glibenclamide

Formulated to alleviate chronic hyperglycaemia to support glycaemic control and target insulin resistance.

Active ingredients
Metformin · Glibenclamide
Route
Oral use
Form
Tablet
Strengths
2.5mg + 400mg · 5mg + 500mg

You will receive a quality generic equivalent of Glucovance, depending on stock.

Prescription and consultation requirements for Glucovance vary by destination and are determined by the fulfilment partner.

Glucovance details

Alternative names
metformin, glyburide
Therapeutic class
Sulfonylurea, Biguanide Combination
Pharmacological class
Antidiabetic Combination
Contraindications
severe renal impairment; acute metabolic acidosis; diabetic ketoacidosis
Minor side effects
diarrhoea; nausea; headache
Moderate side effects
hypoglycaemia; metallic taste; weight gain
Dosage forms
Tablet
Administration route
Oral use
Supply category
Prescription-only medicine (POM)
Originator
Bristol-Myers Squibb
Onset Time
1–2 hours
Duration
12–24 hours
Storage instructions
Store below 25°C.
Drug interactions
Contrast Media; Alcohol; Ciprofloxacin
Age restrictions
Approved for adults.
Serious side effects

lactic acidosis, requires immediate medical attention; severe hypoglycaemia, requires immediate medical attention

Patient summary

formulated to alleviate chronic hyperglycaemia to support glycaemic control and target insulin resistance.

Mechanism of action

Glyburide triggers pancreatic insulin output while metformin minimises hepatic glucose synthesis and enhances receptor sensitivity.

Pregnancy and breastfeeding

TGA Category B/C: Avoid during pregnancy. Glycaemic control with insulin preferred. Breastfeeding: Avoid.

What you will receive

Glucovance is the originator brand name, made by Bristol-Myers Squibb. We use it to identify the medicine and are not affiliated with Bristol-Myers Squibb.

  • The fulfilment partner confirms whether the exact brand or an equivalent containing Metformin / Glibenclamide is offered.
  • The offered brand, manufacturer and dispatch location depend on the product, destination and partner warehouse.
  • Check the final product details at checkout before confirming an order.

How we compare medicine brands and generics