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Glucovance

Glucovance

Metformin · Glibenclamide

Metformin and glibenclamide tablets for type 2 diabetes. The two drugs lower blood sugar by different routes, so one pill does the work of two separate ones.

Active ingredients
Metformin · Glibenclamide
Route
Oral use
Form
Tablet
Strengths
2.5mg + 400mg · 5mg + 500mg

This listing uses Glucovance as a reference name. A generic equivalent is supplied; its exact brand and manufacturer are confirmed before supply.

Prescription and consultation requirements for Glucovance vary by destination and are determined by the fulfilment partner.

Glucovance details

Alternative names
metformin, glyburide
Therapeutic class
Sulfonylurea, Biguanide Combination
Pharmacological class
Antidiabetic Combination
Contraindications
severe renal impairment; acute metabolic acidosis; diabetic ketoacidosis
Minor side effects
diarrhoea; nausea; headache
Moderate side effects
hypoglycaemia; metallic taste; weight gain
Dosage forms
Tablet
Administration route
Oral use
Supply category
Prescription-only medicine (POM)
Originator
Bristol-Myers Squibb
Onset Time
1–2 hours
Duration
12–24 hours
Storage instructions
Store below 25°C.
Drug interactions
Contrast Media; Alcohol; Ciprofloxacin
Age restrictions
Approved for adults.
Serious side effects

lactic acidosis, requires immediate medical attention; severe hypoglycaemia, requires immediate medical attention

Patient summary

Metformin and glibenclamide tablets for type 2 diabetes. The two drugs lower blood sugar by different routes, so one pill does the work of two separate ones.

Mechanism of action

Glyburide triggers pancreatic insulin output while metformin minimises hepatic glucose synthesis and enhances receptor sensitivity.

Pregnancy and breastfeeding

Pregnancy: Avoid during pregnancy. Glycaemic control with insulin preferred. Breastfeeding: Avoid.

What you will receive

Glucovance is used here as a reference originator brand name to identify the medicine. We are not affiliated with the brand owner, and this listing does not offer the originator product.

  • The supplied product is a generic equivalent containing Metformin / Glibenclamide, not the originator brand shown as the reference.
  • The exact generic brand, manufacturer and dispatch location are confirmed based on the product, destination and available manufacturer or partner warehouse.
  • Check the final product details at checkout before confirming an order.

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