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Pirfenex

Pirfenex

Pirfenidone

Pirfenidone tablets for idiopathic pulmonary fibrosis. It suppresses the signals that drive scar tissue formation in the lungs.

All strengths and pack prices
StrengthPackPricePer unit
200mg90 tablets$321.00$3.57
200mg180 tablets$505.00$2.81
200mg270 tablets$630.00$2.33
200mg360 tablets$780.00$2.17
400mg60 tablets$60.00$1.00
400mg120 tablets$114.00$0.95
400mg240 tablets$221.00$0.92
400mg360 tablets$323.00$0.90
600mg30 tablets$30.00$1.00
600mg60 tablets$58.00$0.97
600mg120 tablets$106.00$0.88
600mg240 tablets$192.00$0.80
600mg360 tablets$259.00$0.72
801mg60 tablets$60.00$1.00
801mg120 tablets$108.00$0.90
801mg240 tablets$209.00$0.87
801mg360 tablets$306.00$0.85
Active ingredient
Pirfenidone
Route
Oral use
Form
Tablet
Strengths
200mg · 400mg · 600mg · 801mg

Prescription and consultation requirements for Pirfenex vary by destination and are determined by the fulfilment partner.

Pirfenex details

Alternative names
pirfenidone
Therapeutic class
Antifibrotic Agent
Pharmacological class
Pyridone Antifibrotic
Minor side effects
nausea; vomiting; photosensitivity
Moderate side effects
skin rash; fatigue; dyspepsia
Dosage forms
Tablet
Administration route
Oral use
Manufacturer
Cipla Ltd
Onset time
2–4 weeks
Duration
12 hours
Storage instructions
Store below 25°C.
Drug interactions
Fluvoxamine; Ciprofloxacin; Tobacco
Age restrictions
Approved for adults.
Contraindications

severe hepatic impairment; severe renal impairment requiring dialysis; concurrent fluvoxamine use

Serious side effects

severe drug-induced hepatotoxicity, requires immediate medical attention; angioedema, requires immediate medical attention

Patient summary

Pirfenidone tablets for idiopathic pulmonary fibrosis. It suppresses the signals that drive scar tissue formation in the lungs.

Mechanism of action

Suppresses synthesis of transforming growth factor-beta and tumour necrosis factor-alpha, stopping collagen accumulation inside tissues.

Pregnancy and breastfeeding

Pregnancy: Limited clinical records. Avoid in pregnancy. Breastfeeding: Consult a doctor.