Pirfenex
Pirfenidone tablets for idiopathic pulmonary fibrosis. It suppresses the signals that drive scar tissue formation in the lungs.
- Category
- Pain & Anti-inflammatories
- Active ingredient
- Pirfenidone
- Route
- Oral use
- Form
- Tablet
- Strengths
- 200mg · 400mg · 600mg · 801mg
Prescription and consultation requirements for Pirfenex vary by destination and are determined by the fulfilment partner.
Pirfenex details
- Condition
- Idiopathic Pulmonary Fibrosis
- Alternative names
- pirfenidone
- Therapeutic class
- Antifibrotic Agent
- Pharmacological class
- Pyridone Antifibrotic
- Minor side effects
- nausea; vomiting; photosensitivity
- Moderate side effects
- skin rash; fatigue; dyspepsia
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Manufacturer
- Cipla Ltd
- Onset Time
- 2–4 weeks
- Duration
- 12 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Fluvoxamine; Ciprofloxacin; Tobacco
- Age restrictions
- Approved for adults.
Contraindications
severe hepatic impairment; severe renal impairment requiring dialysis; concurrent fluvoxamine use
Serious side effects
severe drug-induced hepatotoxicity, requires immediate medical attention; angioedema, requires immediate medical attention
Patient summary
Pirfenidone tablets for idiopathic pulmonary fibrosis. It suppresses the signals that drive scar tissue formation in the lungs.
Mechanism of action
Suppresses synthesis of transforming growth factor-beta and tumour necrosis factor-alpha, stopping collagen accumulation inside tissues.
Pregnancy and breastfeeding
Pregnancy: Limited clinical records. Avoid in pregnancy. Breastfeeding: Consult a doctor.