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Prograf

Prograf

Tacrolimus

Tacrolimus tablets to stop organ transplant rejection. It suppresses the immune system's attack on the new organ and requires regular blood level checks.

Active ingredient
Tacrolimus
Route
Oral use
Form
Tablet
Strengths
0.5mg · 1mg · 5mg

This listing uses Prograf as a reference name. A generic equivalent is supplied; its exact brand and manufacturer are confirmed before supply.

Prescription and consultation requirements for Prograf vary by destination and are determined by the fulfilment partner.

Prograf details

Alternative names
tacrolimus
Therapeutic class
Calcineurin Inhibitor
Pharmacological class
Immunosuppressant
Known off-label uses
severe active rheumatoid arthritis
Contraindications
hypersensitivity to tacrolimus
Minor side effects
headache; tremor; nausea
Moderate side effects
renal dysfunction; hypertension; hyperglycaemia
Dosage forms
Tablet
Administration route
Oral use
Supply category
Prescription-only medicine (POM)
Originator
Astellas Pharma
Onset Time
2–4 weeks
Duration
12–24 hours
Storage instructions
Store below 25°C.
Drug interactions
Ketoconazole; Rifampin; Grapefruit
Age restrictions
Approved for children and adults under specialist care.
Serious side effects

severe nephrotoxicity, requires immediate medical attention; severe systemic infections, requires immediate medical attention

Patient summary

Tacrolimus tablets to stop organ transplant rejection. It suppresses the immune system's attack on the new organ and requires regular blood level checks.

Mechanism of action

Binds to intracellular immunophilins to block calcineurin, stopping critical T-cell transcription processes.

Pregnancy and breastfeeding

Pregnancy: Use if potential benefits justify risks. Breastfeeding: Contraindicated.

What you will receive

Prograf is used here as a reference originator brand name to identify the medicine. We are not affiliated with the brand owner, and this listing does not offer the originator product.

  • The supplied product is a generic equivalent containing Tacrolimus, not the originator brand shown as the reference.
  • The exact generic brand, manufacturer and dispatch location are confirmed based on the product, destination and available manufacturer or partner warehouse.
  • Check the final product details at checkout before confirming an order.

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